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BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.
Brook B, Harbeson DJ, Shannon CP, Cai B, He D, Ben-Othman R, Francis F, Huang J, Varankovich N, Liu A, Bao W, Bjerregaard-Andersen M, Schaltz-Buchholzer F, Sanca L, Golding CN, Larsen KL, Levy O, Kampmann B; EPIC Consortium; Tan R, Charles A, Wynn JL, Shann F, Aaby P, Benn CS, Tebbutt SJ, Kollmann TR, Amenyogbe N. Brook B, et al. Sci Transl Med. 2020 May 6;12(542):eaax4517. doi: 10.1126/scitranslmed.aax4517. Sci Transl Med. 2020. PMID: 32376769 Free PMC article.
Probiotic Studies in Neonatal Mice Using Gavage.
Francis F, Varankovich N, Brook B, Amenyogbe N, Ben-Othman R, Cai B, Harbeson D, Liu AC, Dai B, McErlane S, Andrews K, Kollmann TR, Panigrahi P. Francis F, et al. Among authors: brook b. J Vis Exp. 2019 Jan 27;(143). doi: 10.3791/59074. J Vis Exp. 2019. PMID: 30741256
A Controlled Mouse Model for Neonatal Polymicrobial Sepsis.
Brook B, Amenyogbe N, Ben-Othman R, Cai B, Harbeson D, Francis F, Liu AC, Varankovich N, Wynn J, Kollmann TR. Brook B, et al. J Vis Exp. 2019 Jan 27;(143). doi: 10.3791/58574. J Vis Exp. 2019. PMID: 30741260
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice.
Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Cavazzoni CB, Brook B, Barman S, Chen J, Diray-Arce J, Doss-Gollin S, De Leon M, Prevost-Reilly A, Chew K, Menon M, Song K, Xu AZ, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Sherman AC, Baden LR, Ernst RK, Dillen C, Weston SM, Johnson RM, Hammond HL, Mayer R, Burke A, Bottazzi ME, Hotez PJ, Strych U, Chang A, Yu J, Sage PT, Barouch DH, Dhe-Paganon S, Zanoni I, Ozonoff A, Frieman MB, Levy O, Dowling DJ. Nanishi E, et al. Among authors: brook b. Sci Transl Med. 2022 Jan 26;14(629):eabj5305. doi: 10.1126/scitranslmed.abj5305. Epub 2022 Jan 26. Sci Transl Med. 2022. PMID: 34783582 Free PMC article.
Shaping Neonatal Immunization by Tuning the Delivery of Synergistic Adjuvants via Nanocarriers.
Barman S, Borriello F, Brook B, Pietrasanta C, De Leon M, Sweitzer C, Menon M, van Haren SD, Soni D, Saito Y, Nanishi E, Yi S, Bobbala S, Levy O, Scott EA, Dowling DJ. Barman S, et al. Among authors: brook b. ACS Chem Biol. 2022 Sep 16;17(9):2559-2571. doi: 10.1021/acschembio.2c00497. Epub 2022 Aug 26. ACS Chem Biol. 2022. PMID: 36028220 Free PMC article.
The mRNA vaccine BNT162b2 demonstrates impaired TH1 immunogenicity in human elders in vitro and aged mice in vivo.
Brook B, Fatou B, Kumar Checkervarty A, Barman S, Sweitzer C, Bosco AN, Sherman AC, Baden LR, Morrocchi E, Sanchez-Schmitz G, Palma P, Nanishi E, O'Meara TR, McGrath ME, Frieman MB, Soni D, van Haren SD, Ozonoff A, Diray-Arce J, Steen H, Dowling DJ, Levy O. Brook B, et al. Res Sq [Preprint]. 2022 Dec 21:rs.3.rs-2395118. doi: 10.21203/rs.3.rs-2395118/v1. Res Sq. 2022. PMID: 36597547 Free PMC article. Preprint.
185 results