Itzhaki L - Search Results

1

Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction.

Strizhak AV, Babii O, Afonin S, Bakanovich I, Pantelejevs T, Xu W, Fowler E, Eapen R, Sharma K, Platonov MO, Hurmach VV, Itzhaki L, Hyvönen M, Ulrich AS, Spring DR, Komarov IV. Strizhak AV, et al. Among authors: itzhaki l. Org Biomol Chem. 2020 Jul 22;18(28):5359-5369. doi: 10.1039/d0ob00831a. Org Biomol Chem. 2020. PMID: 32390036 Free article.

2

Single-molecule FRET reveals hidden complexity in a protein energy landscape.

Tsytlonok M, Ibrahim SM, Rowling PJE, Xu W, Ruedas-Rama MJ, Orte A, Klenerman D, Itzhaki LS. Tsytlonok M, et al. Structure. 2015 Jan 6;23(1):190-198. doi: 10.1016/j.str.2014.10.023. Structure. 2015. PMID: 25565106 Free PMC article.

3

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell.

Chattopadhyay A, O'Connor CJ, Zhang F, Galvagnion C, Galloway WR, Tan YS, Stokes JE, Rahman T, Verma C, Spring DR, Itzhaki LS. Chattopadhyay A, et al. Sci Rep. 2016 Apr 5;6:23732. doi: 10.1038/srep23732. Sci Rep. 2016. PMID: 27046077 Free PMC article.

4

Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer.

Wiedmann MM, Tan YS, Wu Y, Aibara S, Xu W, Sore HF, Verma CS, Itzhaki L, Stewart M, Brenton JD, Spring DR. Wiedmann MM, et al. Among authors: itzhaki l. Angew Chem Int Ed Engl. 2017 Jan 9;56(2):524-529. doi: 10.1002/anie.201609427. Epub 2016 Dec 5. Angew Chem Int Ed Engl. 2017. PMID: 27918136 Free PMC article.

5

Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.

Xu W, Lau YH, Fischer G, Tan YS, Chattopadhyay A, de la Roche M, Hyvönen M, Verma C, Spring DR, Itzhaki LS. Xu W, et al. J Am Chem Soc. 2017 Feb 15;139(6):2245-2256. doi: 10.1021/jacs.6b10234. Epub 2017 Feb 7. J Am Chem Soc. 2017. PMID: 28084734 Free PMC article.

6

A New Methodology for Incorporating Chiral Linkers into Stapled Peptides.

Serrano JC, Sipthorp J, Xu W, Itzhaki LS, Ley SV. Serrano JC, et al. Chembiochem. 2017 Jun 19;18(12):1066-1071. doi: 10.1002/cbic.201700075. Epub 2017 May 18. Chembiochem. 2017. PMID: 28388005 Free PMC article.

7

Kinetic and thermodynamic effects of phosphorylation on p53 binding to MDM2.

Yadahalli S, Neira JL, Johnson CM, Tan YS, Rowling PJE, Chattopadhyay A, Verma CS, Itzhaki LS. Yadahalli S, et al. Among authors: itzhaki ls. Sci Rep. 2019 Jan 24;9(1):693. doi: 10.1038/s41598-018-36589-5. Sci Rep. 2019. PMID: 30679555 Free PMC article.

8

Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides.

Wu Y, Kaur A, Fowler E, Wiedmann MM, Young R, Galloway WRJD, Olsen L, Sore HF, Chattopadhyay A, Kwan TT, Xu W, Walsh SJ, de Andrade P, Janecek M, Arumugam S, Itzhaki LS, Lau YH, Spring DR. Wu Y, et al. Among authors: itzhaki ls. ACS Chem Biol. 2019 Mar 15;14(3):526-533. doi: 10.1021/acschembio.9b00063. Epub 2019 Feb 7. ACS Chem Biol. 2019. PMID: 30702850

9

Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides.

Charoenpattarapreeda J, Tan YS, Iegre J, Walsh SJ, Fowler E, Eapen RS, Wu Y, Sore HF, Verma CS, Itzhaki L, Spring DR. Charoenpattarapreeda J, et al. Among authors: itzhaki l. Chem Commun (Camb). 2019 Jul 14;55(55):7914-7917. doi: 10.1039/c9cc04022f. Epub 2019 Jun 21. Chem Commun (Camb). 2019. PMID: 31225847

10

Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry.

Sharma K, Strizhak AV, Fowler E, Wang X, Xu W, Hatt Jensen C, Wu Y, Sore HF, Lau YH, Hyvönen M, Itzhaki LS, Spring DR. Sharma K, et al. Org Biomol Chem. 2019 Aug 28;17(34):8014-8018. doi: 10.1039/c9ob01745c. Org Biomol Chem. 2019. PMID: 31418442

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

118 results

Search Page