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Identification of the human Cytochrome P450 enzymes (P450s) responsible for metabolizing infigratinib to its pharmacologically active Metabolites, BHS697, and CQM157, and assessment of their in vitro inhibition of P450s and UDP-glucuronosyltransferases (UGTs).
Liu S, Zhao S, Zhang X, Chun Yong Chan E, Wang Z, Li H, Tian X. Liu S, et al. Among authors: li h. Biochem Pharmacol. 2024 Jun 22:116390. doi: 10.1016/j.bcp.2024.116390. Online ahead of print. Biochem Pharmacol. 2024. PMID: 38914316
Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner.
Yang BL, Long YY, Lei Q, Gao F, Ren WX, Cao YL, Wu D, Xu LY, Qu J, Li H, Yu YL, Zhang AY, Wang S, Wang HX, Chen ZC, Li QB. Yang BL, et al. Among authors: li h. Acta Pharmacol Sin. 2024 Jun 24. doi: 10.1038/s41401-024-01327-3. Online ahead of print. Acta Pharmacol Sin. 2024. PMID: 38914677
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