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Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth.
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, Kar G, Vento-Tormo R, Hagai T, Chen X, Haniffa MA, Shields JD, Teichmann SA. Davidson S, et al. Among authors: shields jd. Cell Rep. 2020 May 19;31(7):107628. doi: 10.1016/j.celrep.2020.107628. Cell Rep. 2020. PMID: 32433953 Free PMC article.
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation.
Miragaia RJ, Gomes T, Chomka A, Jardine L, Riedel A, Hegazy AN, Whibley N, Tucci A, Chen X, Lindeman I, Emerton G, Krausgruber T, Shields J, Haniffa M, Powrie F, Teichmann SA. Miragaia RJ, et al. Immunity. 2019 Feb 19;50(2):493-504.e7. doi: 10.1016/j.immuni.2019.01.001. Epub 2019 Feb 5. Immunity. 2019. PMID: 30737144 Free PMC article.
Tumors induce de novo steroid biosynthesis in T cells to evade immunity.
Mahata B, Pramanik J, van der Weyden L, Polanski K, Kar G, Riedel A, Chen X, Fonseca NA, Kundu K, Campos LS, Ryder E, Duddy G, Walczak I, Okkenhaug K, Adams DJ, Shields JD, Teichmann SA. Mahata B, et al. Among authors: shields jd. Nat Commun. 2020 Jul 17;11(1):3588. doi: 10.1038/s41467-020-17339-6. Nat Commun. 2020. PMID: 32680985 Free PMC article.
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung.
Schuijs MJ, Png S, Richard AC, Tsyben A, Hamm G, Stockis J, Garcia C, Pinaud S, Nicholls A, Ros XR, Su J, Eldridge MD, Riedel A, Serrao EM, Rodewald HR, Mack M, Shields JD, Cohen ES, McKenzie ANJ, Goodwin RJA, Brindle KM, Marioni JC, Halim TYF. Schuijs MJ, et al. Among authors: shields jd. Nat Immunol. 2020 Sep;21(9):998-1009. doi: 10.1038/s41590-020-0745-y. Epub 2020 Aug 3. Nat Immunol. 2020. PMID: 32747815 Free PMC article.
Stromal regulation of tumor-associated lymphatics.
Munir H, Mazzaglia C, Shields JD. Munir H, et al. Among authors: shields jd. Adv Drug Deliv Rev. 2020;161-162:75-89. doi: 10.1016/j.addr.2020.08.001. Epub 2020 Aug 9. Adv Drug Deliv Rev. 2020. PMID: 32783989
Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma.
Riedel A, Helal M, Pedro L, Swietlik JJ, Shorthouse D, Schmitz W, Haas L, Young T, da Costa ASH, Davidson S, Bhandare P, Wolf E, Hall BA, Frezza C, Oskarsson T, Shields JD. Riedel A, et al. Among authors: shields jd. Cancer Immunol Res. 2022 Apr 1;10(4):482-497. doi: 10.1158/2326-6066.CIR-21-0778. Cancer Immunol Res. 2022. PMID: 35362044 Free PMC article.
104 results