Pitson SM - Search Results

1

ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism.

Boyle ST, Poltavets V, Kular J, Pyne NT, Sandow JJ, Lewis AC, Murphy KJ, Kolesnikoff N, Moretti PAB, Tea MN, Tergaonkar V, Timpson P, Pitson SM, Webb AI, Whitfield RJ, Lopez AF, Kochetkova M, Samuel MS. Boyle ST, et al. Among authors: pitson sm. Nat Cell Biol. 2020 Jul;22(7):882-895. doi: 10.1038/s41556-020-0523-y. Epub 2020 May 25. Nat Cell Biol. 2020. PMID: 32451439

2

Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase.

Pitson SM, Moretti PA, Zebol JR, Xia P, Gamble JR, Vadas MA, D'Andrea RJ, Wattenberg BW. Pitson SM, et al. J Biol Chem. 2000 Oct 27;275(43):33945-50. doi: 10.1074/jbc.M006176200. J Biol Chem. 2000. PMID: 10944534 Free article.

3

An oncogenic role of sphingosine kinase.

Xia P, Gamble JR, Wang L, Pitson SM, Moretti PA, Wattenberg BW, D'Andrea RJ, Vadas MA. Xia P, et al. Among authors: pitson sm. Curr Biol. 2000 Nov 30;10(23):1527-30. doi: 10.1016/s0960-9822(00)00834-4. Curr Biol. 2000. PMID: 11114522 Free article.

4

Sphingosine activates protein kinase A type II by a novel cAMP-independent mechanism.

Ma Y, Pitson S, Hercus T, Murphy J, Lopez A, Woodcock J. Ma Y, et al. J Biol Chem. 2005 Jul 15;280(28):26011-7. doi: 10.1074/jbc.M409081200. Epub 2005 May 9. J Biol Chem. 2005. PMID: 15883165 Free article.

5

Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their function.

Woodcock JM, Ma Y, Coolen C, Pham D, Jones C, Lopez AF, Pitson SM. Woodcock JM, et al. Among authors: pitson sm. Cell Signal. 2010 Sep;22(9):1291-9. doi: 10.1016/j.cellsig.2010.04.004. Epub 2010 Apr 18. Cell Signal. 2010. PMID: 20403428

6

The GM-CSF receptor family: mechanism of activation and implications for disease.

Hercus TR, Broughton SE, Ekert PG, Ramshaw HS, Perugini M, Grimbaldeston M, Woodcock JM, Thomas D, Pitson S, Hughes T, D'Andrea RJ, Parker MW, Lopez AF. Hercus TR, et al. Growth Factors. 2012 Apr;30(2):63-75. doi: 10.3109/08977194.2011.649919. Epub 2012 Jan 18. Growth Factors. 2012. PMID: 22257375 Review.

7

Molecular targets of FTY720 (fingolimod).

Pitman MR, Woodcock JM, Lopez AF, Pitson SM. Pitman MR, et al. Among authors: pitson sm. Curr Mol Med. 2012 Dec;12(10):1207-19. doi: 10.2174/156652412803833599. Curr Mol Med. 2012. PMID: 22834825 Review.

8

Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival.

Thomas D, Powell JA, Green BD, Barry EF, Ma Y, Woodcock J, Fitter S, Zannettino AC, Pitson SM, Hughes TP, Lopez AF, Shepherd PR, Wei AH, Ekert PG, Guthridge MA. Thomas D, et al. Among authors: pitson sm. PLoS Biol. 2013;11(3):e1001515. doi: 10.1371/journal.pbio.1001515. Epub 2013 Mar 19. PLoS Biol. 2013. PMID: 23526884 Free PMC article.

9

Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics.

Woodcock JM, Coolen C, Goodwin KL, Baek DJ, Bittman R, Samuel MS, Pitson SM, Lopez AF. Woodcock JM, et al. Among authors: pitson sm. Oncotarget. 2015 Jun 10;6(16):14522-36. doi: 10.18632/oncotarget.3995. Oncotarget. 2015. PMID: 25971334 Free PMC article.

10

Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis.

Parham KA, Zebol JR, Tooley KL, Sun WY, Moldenhauer LM, Cockshell MP, Gliddon BL, Moretti PA, Tigyi G, Pitson SM, Bonder CS. Parham KA, et al. Among authors: pitson sm. FASEB J. 2015 Sep;29(9):3638-53. doi: 10.1096/fj.14-261289. Epub 2015 May 18. FASEB J. 2015. PMID: 25985799 Free PMC article.

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