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Generation and infusion of multi-antigen-specific T cells to prevent complications early after T-cell depleted allogeneic stem cell transplantation-a phase I/II study.
Roex MCJ, van Balen P, Germeroth L, Hageman L, van Egmond E, Veld SAJ, Hoogstraten C, van Liempt E, Zwaginga JJ, de Wreede LC, Meij P, Vossen ACTM, Danhof S, Einsele H, Schaafsma MR, Veelken H, Halkes CJM, Jedema I, Falkenburg JHF. Roex MCJ, et al. Among authors: germeroth l. Leukemia. 2020 Mar;34(3):831-844. doi: 10.1038/s41375-019-0600-z. Epub 2019 Oct 17. Leukemia. 2020. PMID: 31624377 Clinical Trial.
Tracking the progeny of adoptively transferred virus-specific T cells in patients posttransplant using TCR sequencing.
Huisman W, Roex MCJ, Hageman L, Koster EAS, Veld SAJ, Hoogstraten C, van Balen P, van Egmond HM, van Bergen CAM, Einsele H, Germeroth L, Amsen D, Falkenburg JHF, Jedema I. Huisman W, et al. Among authors: germeroth l. Blood Adv. 2023 Mar 14;7(5):812-827. doi: 10.1182/bloodadvances.2022007270. Blood Adv. 2023. PMID: 36121440 Free PMC article.
The simultaneous isolation of multiple high and low frequent T-cell populations from donor peripheral blood mononuclear cells using the major histocompatibility complex I-Streptamer isolation technology.
Roex MCJ, Hageman L, Heemskerk MT, Veld SAJ, van Liempt E, Kester MGD, Germeroth L, Stemberger C, Falkenburg JHF, Jedema I. Roex MCJ, et al. Among authors: germeroth l. Cytotherapy. 2018 Apr;20(4):543-555. doi: 10.1016/j.jcyt.2018.01.008. Epub 2018 Feb 12. Cytotherapy. 2018. PMID: 29449085
Lowest numbers of primary CD8(+) T cells can reconstitute protective immunity upon adoptive immunotherapy.
Stemberger C, Graef P, Odendahl M, Albrecht J, Dössinger G, Anderl F, Buchholz VR, Gasteiger G, Schiemann M, Grigoleit GU, Schuster FR, Borkhardt A, Versluys B, Tonn T, Seifried E, Einsele H, Germeroth L, Busch DH, Neuenhahn M. Stemberger C, et al. Among authors: germeroth l. Blood. 2014 Jul 24;124(4):628-37. doi: 10.1182/blood-2013-12-547349. Epub 2014 May 22. Blood. 2014. PMID: 24855206 Free article.
Clinical-scale isolation of 'minimally manipulated' cytomegalovirus-specific donor lymphocytes for the treatment of refractory cytomegalovirus disease.
Odendahl M, Grigoleit GU, Bönig H, Neuenhahn M, Albrecht J, Anderl F, Germeroth L, Schmitz M, Bornhäuser M, Einsele H, Seifried E, Busch DH, Tonn T. Odendahl M, et al. Among authors: germeroth l. Cytotherapy. 2014 Sep;16(9):1245-56. doi: 10.1016/j.jcyt.2014.05.023. Cytotherapy. 2014. PMID: 25108651 Free article.
Expamers: a new technology to control T cell activation.
Poltorak MP, Graef P, Tschulik C, Wagner M, Cletiu V, Dreher S, Borjan B, Fraessle SP, Effenberger M, Turk M, Busch DH, Plitzko J, Kugler DG, Ragan S, Schmidt T, Stemberger C, Germeroth L. Poltorak MP, et al. Among authors: germeroth l. Sci Rep. 2020 Oct 20;10(1):17832. doi: 10.1038/s41598-020-74595-8. Sci Rep. 2020. PMID: 33082362 Free PMC article.
Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation.
Radisch S, Poltorak MP, Wagner M, Cletiu V, Radisch C, Treise I, Pann S, Weigt A, Artner S, Dreher S, Fechner F, Borjan B, Fraessle SP, Effenberger M, Benke E, Navratil G, Hentschel N, Busch DH, Schmidt T, Stemberger C, Germeroth L. Radisch S, et al. Among authors: germeroth l. Sci Rep. 2022 Apr 21;12(1):6572. doi: 10.1038/s41598-022-10320-x. Sci Rep. 2022. PMID: 35449227 Free PMC article.
Transfer of minimally manipulated CMV-specific T cells from stem cell or third-party donors to treat CMV infection after allo-HSCT.
Neuenhahn M, Albrecht J, Odendahl M, Schlott F, Dössinger G, Schiemann M, Lakshmipathi S, Martin K, Bunjes D, Harsdorf S, Weissinger EM, Menzel H, Verbeek M, Uharek L, Kröger N, Wagner E, Kobbe G, Schroeder T, Schmitt M, Held G, Herr W, Germeroth L, Bonig H, Tonn T, Einsele H, Busch DH, Grigoleit GU. Neuenhahn M, et al. Among authors: germeroth l. Leukemia. 2017 Oct;31(10):2161-2171. doi: 10.1038/leu.2017.16. Epub 2017 Jan 16. Leukemia. 2017. PMID: 28090089 Clinical Trial.
56 results