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An Early mtUPR: Redistribution of the Nuclear Transcription Factor Rox1 to Mitochondria Protects against Intramitochondrial Proteotoxic Aggregates.
Poveda-Huertes D, Matic S, Marada A, Habernig L, Licheva M, Myketin L, Gilsbach R, Tosal-Castano S, Papinski D, Mulica P, Kretz O, Kücükköse C, Taskin AA, Hein L, Kraft C, Büttner S, Meisinger C, Vögtle FN. Poveda-Huertes D, et al. Among authors: kucukkose c. Mol Cell. 2020 Jan 2;77(1):180-188.e9. doi: 10.1016/j.molcel.2019.09.026. Epub 2019 Oct 17. Mol Cell. 2020. PMID: 31630969 Free PMC article.
Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery.
Walter C, Marada A, Suhm T, Ernsberger R, Muders V, Kücükköse C, Sánchez-Martín P, Hu Z, Aich A, Loroch S, Solari FA, Poveda-Huertes D, Schwierzok A, Pommerening H, Matic S, Brix J, Sickmann A, Kraft C, Dengjel J, Dennerlein S, Brummer T, Vögtle FN, Meisinger C. Walter C, et al. Among authors: kucukkose c. Nat Commun. 2021 Jul 13;12(1):4284. doi: 10.1038/s41467-021-24426-9. Nat Commun. 2021. PMID: 34257281 Free PMC article.
Landscape of submitochondrial protein distribution.
Vögtle FN, Burkhart JM, Gonczarowska-Jorge H, Kücükköse C, Taskin AA, Kopczynski D, Ahrends R, Mossmann D, Sickmann A, Zahedi RP, Meisinger C. Vögtle FN, et al. Among authors: kucukkose c. Nat Commun. 2017 Aug 18;8(1):290. doi: 10.1038/s41467-017-00359-0. Nat Commun. 2017. PMID: 28819139 Free PMC article.
Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood.
Vögtle FN, Brändl B, Larson A, Pendziwiat M, Friederich MW, White SM, Basinger A, Kücükköse C, Muhle H, Jähn JA, Keminer O, Helbig KL, Delto CF, Myketin L, Mossmann D, Burger N, Miyake N, Burnett A, van Baalen A, Lovell MA, Matsumoto N, Walsh M, Yu HC, Shinde DN, Stephani U, Van Hove JLK, Müller FJ, Helbig I. Vögtle FN, et al. Among authors: kucukkose c. Am J Hum Genet. 2018 Apr 5;102(4):557-573. doi: 10.1016/j.ajhg.2018.02.014. Epub 2018 Mar 22. Am J Hum Genet. 2018. PMID: 29576218 Free PMC article.