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A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.
Pattwell SS, Arora S, Cimino PJ, Ozawa T, Szulzewsky F, Hoellerbauer P, Bonifert T, Hoffstrom BG, Boiani NE, Bolouri H, Correnti CE, Oldrini B, Silber JR, Squatrito M, Paddison PJ, Holland EC. Pattwell SS, et al. Among authors: squatrito m. Nat Commun. 2020 Jun 12;11(1):2977. doi: 10.1038/s41467-020-16786-5. Nat Commun. 2020. PMID: 32532995 Free PMC article.
Take It Down a NOTCH in Forebrain Tumors.
Oldrini B, Schuhmacher AJ, Squatrito M. Oldrini B, et al. Among authors: squatrito m. Cancer Cell. 2015 Dec 14;28(6):681-682. doi: 10.1016/j.ccell.2015.11.008. Cancer Cell. 2015. PMID: 26678333 Free article.
Glioma formation, cancer stem cells, and akt signaling.
Hambardzumyan D, Squatrito M, Carbajal E, Holland EC. Hambardzumyan D, et al. Among authors: squatrito m. Stem Cell Rev. 2008 Sep;4(3):203-10. doi: 10.1007/s12015-008-9021-5. Stem Cell Rev. 2008. PMID: 18595010 Review.
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas.
Oldrini B, Vaquero-Siguero N, Mu Q, Kroon P, Zhang Y, Galán-Ganga M, Bao Z, Wang Z, Liu H, Sa JK, Zhao J, Kim H, Rodriguez-Perales S, Nam DH, Verhaak RGW, Rabadan R, Jiang T, Wang J, Squatrito M. Oldrini B, et al. Among authors: squatrito m. Nat Commun. 2020 Aug 4;11(1):3883. doi: 10.1038/s41467-020-17717-0. Nat Commun. 2020. PMID: 32753598 Free PMC article.
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer.
Oldrini B, Hsieh WY, Erdjument-Bromage H, Codega P, Carro MS, Curiel-García A, Campos C, Pourmaleki M, Grommes C, Vivanco I, Rohle D, Bielski CM, Taylor BS, Hollmann TJ, Rosenblum M, Tempst P, Blenis J, Squatrito M, Mellinghoff IK. Oldrini B, et al. Among authors: squatrito m. Nat Commun. 2017 Dec 11;8(1):2035. doi: 10.1038/s41467-017-02185-w. Nat Commun. 2017. PMID: 29229958 Free PMC article.
Radiation resistance and stem-like cells in brain tumors.
Hambardzumyan D, Squatrito M, Holland EC. Hambardzumyan D, et al. Among authors: squatrito m. Cancer Cell. 2006 Dec;10(6):454-6. doi: 10.1016/j.ccr.2006.11.008. Cancer Cell. 2006. PMID: 17157785 Free article.
48 results