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Effects of Toxoplasma gondii infection on the brain.
Carruthers VB, Suzuki Y. Carruthers VB, et al. Schizophr Bull. 2007 May;33(3):745-51. doi: 10.1093/schbul/sbm008. Epub 2007 Feb 23. Schizophr Bull. 2007. PMID: 17322557 Free PMC article. Review.
Kinetic modeling of Toxoplasma gondii invasion.
Kafsack BF, Carruthers VB, Pineda FJ. Kafsack BF, et al. Among authors: carruthers vb. J Theor Biol. 2007 Dec 21;249(4):817-25. doi: 10.1016/j.jtbi.2007.09.008. Epub 2007 Sep 14. J Theor Biol. 2007. PMID: 17942124 Free PMC article.
Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis.
Doggett JS, Nilsen A, Forquer I, Wegmann KW, Jones-Brando L, Yolken RH, Bordón C, Charman SA, Katneni K, Schultz T, Burrows JN, Hinrichs DJ, Meunier B, Carruthers VB, Riscoe MK. Doggett JS, et al. Among authors: carruthers vb. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15936-41. doi: 10.1073/pnas.1208069109. Epub 2012 Sep 10. Proc Natl Acad Sci U S A. 2012. PMID: 23019377 Free PMC article.
Cerebral complement C1q activation in chronic Toxoplasma infection.
Xiao J, Li Y, Gressitt KL, He H, Kannan G, Schultz TL, Svezhova N, Carruthers VB, Pletnikov MV, Yolken RH, Severance EG. Xiao J, et al. Among authors: carruthers vb. Brain Behav Immun. 2016 Nov;58:52-56. doi: 10.1016/j.bbi.2016.04.009. Epub 2016 Apr 22. Brain Behav Immun. 2016. PMID: 27109609 Free PMC article.
Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.
Vidadala RS, Rivas KL, Ojo KK, Hulverson MA, Zambriski JA, Bruzual I, Schultz TL, Huang W, Zhang Z, Scheele S, DeRocher AE, Choi R, Barrett LK, Siddaramaiah LK, Hol WG, Fan E, Merritt EA, Parsons M, Freiberg G, Marsh K, Kempf DJ, Carruthers VB, Isoherranen N, Doggett JS, Van Voorhis WC, Maly DJ. Vidadala RS, et al. Among authors: carruthers vb. J Med Chem. 2016 Jul 14;59(13):6531-46. doi: 10.1021/acs.jmedchem.6b00760. Epub 2016 Jul 1. J Med Chem. 2016. PMID: 27309760 Free PMC article.
145 results