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The Hedgehog signalling pathway regulates autophagy.
Jimenez-Sanchez M, Menzies FM, Chang YY, Simecek N, Neufeld TP, Rubinsztein DC. Jimenez-Sanchez M, et al. Among authors: menzies fm. Nat Commun. 2012;3:1200. doi: 10.1038/ncomms2212. Nat Commun. 2012. PMID: 23149744 Free PMC article.
Polyglutamine tracts regulate beclin 1-dependent autophagy.
Ashkenazi A, Bento CF, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, Squitieri F, Hardenberg MC, Imarisio S, Menzies FM, Rubinsztein DC. Ashkenazi A, et al. Among authors: menzies fm. Nature. 2017 May 4;545(7652):108-111. doi: 10.1038/nature22078. Epub 2017 Apr 26. Nature. 2017. PMID: 28445460 Free PMC article.
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A.
Son SM, Park SJ, Lee H, Siddiqi F, Lee JE, Menzies FM, Rubinsztein DC. Son SM, et al. Among authors: menzies fm. Cell Metab. 2019 Jan 8;29(1):192-201.e7. doi: 10.1016/j.cmet.2018.08.013. Epub 2018 Sep 6. Cell Metab. 2019. PMID: 30197302 Free PMC article.
Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.
Siddiqi FH, Menzies FM, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, Ricketts T, Jimenez-Sanchez M, Esteban MA, Lai L, Tortorella MD, Luo Z, Liu H, Metzakopian E, Fernandes HJR, Bassett A, Karran E, Miller BL, Fleming A, Rubinsztein DC. Siddiqi FH, et al. Among authors: menzies fm. Nat Commun. 2019 Apr 18;10(1):1817. doi: 10.1038/s41467-019-09494-2. Nat Commun. 2019. PMID: 31000720 Free PMC article.
68 results