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Corrigendum to "DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits". Neurobiology of Disease 134 (2020) 104629.
Solti K, Kuan WL, Fórizs B, Kustos G, Mihály J, Varga Z, Herberth B, Moravcsik É, Kiss R, Kárpáti M, Mikes A, Zhao Y, Imre T, Rochet JC, Aigbirhio F, Williams-Gray CH, Barker RA, Tóth G. Solti K, et al. Among authors: rochet jc. Neurobiol Dis. 2020 Aug;142:104971. doi: 10.1016/j.nbd.2020.104971. Epub 2020 Jun 20. Neurobiol Dis. 2020. PMID: 32576487 Free article. No abstract available.
DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits.
Solti K, Kuan WL, Fórizs B, Kustos G, Mihály J, Varga Z, Herberth B, Moravcsik É, Kiss R, Kárpáti M, Mikes A, Zhao Y, Imre T, Rochet JC, Aigbirhio F, Williams-Gray CH, Barker RA, Tóth G. Solti K, et al. Among authors: rochet jc. Neurobiol Dis. 2020 Feb;134:104629. doi: 10.1016/j.nbd.2019.104629. Epub 2019 Nov 11. Neurobiol Dis. 2020. PMID: 31669752 Free article.
Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways.
Anandhan A, Rodriguez-Rocha H, Bohovych I, Griggs AM, Zavala-Flores L, Reyes-Reyes EM, Seravalli J, Stanciu LA, Lee J, Rochet JC, Khalimonchuk O, Franco R. Anandhan A, et al. Among authors: rochet jc. Neurobiol Dis. 2015 Sep;81:76-92. doi: 10.1016/j.nbd.2014.11.018. Epub 2014 Dec 8. Neurobiol Dis. 2015. PMID: 25497688 Free PMC article.
Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form.
Collier TJ, Srivastava KR, Justman C, Grammatopoulous T, Hutter-Paier B, Prokesch M, Havas D, Rochet JC, Liu F, Jock K, de Oliveira P, Stirtz GL, Dettmer U, Sortwell CE, Feany MB, Lansbury P, Lapidus L, Paumier KL. Collier TJ, et al. Among authors: rochet jc. Neurobiol Dis. 2017 Oct;106:191-204. doi: 10.1016/j.nbd.2017.07.007. Epub 2017 Jul 12. Neurobiol Dis. 2017. PMID: 28711409 Free PMC article.
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions.
Tóth G, Neumann T, Berthet A, Masliah E, Spencer B, Tao J, Jobling MF, Gardai SJ, Bertoncini CW, Cremades N, Bova M, Ballaron S, Chen XH, Mao W, Nguyen P, Tabios MC, Tambe MA, Rochet JC, Junker HD, Schwizer D, Sekul R, Ott I, Anderson JP, Szoke B, Hoffman W, Christodoulou J, Yednock T, Agard DA, Schenk D, McConlogue L. Tóth G, et al. Among authors: rochet jc. Sci Rep. 2019 Nov 18;9(1):16947. doi: 10.1038/s41598-019-52598-4. Sci Rep. 2019. PMID: 31740740 Free PMC article.
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.
Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, Callaway K, Anderson JP, Jobling MF, Buell AK, Yednock TA, Knowles TP, Vendruscolo M, Christodoulou J, Dobson CM, Schenk D, McConlogue L. Tóth G, et al. Among authors: rochet jc. PLoS One. 2014 Feb 14;9(2):e87133. doi: 10.1371/journal.pone.0087133. eCollection 2014. PLoS One. 2014. PMID: 24551051 Free PMC article.
98 results