Yin T - Search Results

1

Microglia TREM2^R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels.

Ren S, Yao W, Tambini MD, Yin T, Norris KA, D'Adamio L. Ren S, et al. Among authors: yin t. Elife. 2020 Jun 24;9:e57513. doi: 10.7554/eLife.57513. Elife. 2020. PMID: 32579116 Free PMC article.

2

The Familial dementia gene ITM2b/BRI2 facilitates glutamate transmission via both presynaptic and postsynaptic mechanisms.

Yao W, Yin T, Tambini MD, D'Adamio L. Yao W, et al. Among authors: yin t. Sci Rep. 2019 Mar 19;9(1):4862. doi: 10.1038/s41598-019-41340-9. Sci Rep. 2019. PMID: 30890756 Free PMC article.

3

Danish and British dementia ITM2b/BRI2 mutations reduce BRI2 protein stability and impair glutamatergic synaptic transmission.

Yin T, Yao W, Lemenze AD, D'Adamio L. Yin T, et al. J Biol Chem. 2021 Jan-Jun;296:100054. doi: 10.1074/jbc.RA120.015679. Epub 2020 Nov 22. J Biol Chem. 2021. PMID: 33172889 Free PMC article.

4

TNF-α-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young Trem2^R47H rats.

Ren S, Breuillaud L, Yao W, Yin T, Norris KA, Zehntner SP, D'Adamio L. Ren S, et al. Among authors: yin t. J Biol Chem. 2021 Jan-Jun;296:100089. doi: 10.1074/jbc.RA120.016395. Epub 2020 Nov 21. J Biol Chem. 2021. PMID: 33434745 Free PMC article.

5

A familial Danish dementia rat shows impaired presynaptic and postsynaptic glutamatergic transmission.

Yin T, Yao W, Norris KA, D'Adamio L. Yin T, et al. J Biol Chem. 2021 Sep;297(3):101089. doi: 10.1016/j.jbc.2021.101089. Epub 2021 Aug 18. J Biol Chem. 2021. PMID: 34416235 Free PMC article.

6

Initial assessment of the spatial learning, reversal, and sequencing task capabilities of knock-in rats with humanizing mutations in the Aβ-coding region of App.

Pham H, Yin T, D'Adamio L. Pham H, et al. Among authors: yin t. PLoS One. 2022 May 4;17(5):e0263546. doi: 10.1371/journal.pone.0263546. eCollection 2022. PLoS One. 2022. PMID: 35507596 Free PMC article.

7

Late-long-term potentiation magnitude, but not Aβ levels and amyloid pathology, is associated with behavioral performance in a rat knock-in model of Alzheimer disease.

Yesiltepe M, Yin T, Tambini MD, Breuillaud L, Zehntner SP, D'Adamio L. Yesiltepe M, et al. Among authors: yin t. Front Aging Neurosci. 2022 Nov 11;14:1040576. doi: 10.3389/fnagi.2022.1040576. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36438008 Free PMC article.

8

Aβ43 levels determine the onset of pathological amyloid deposition.

Tambini MD, Yin T, Yesiltepe M, Breuillaud L, Zehntner SP, d'Abramo C, Giliberto L, D'Adamio L. Tambini MD, et al. Among authors: yin t. J Biol Chem. 2023 Jul;299(7):104868. doi: 10.1016/j.jbc.2023.104868. Epub 2023 May 29. J Biol Chem. 2023. PMID: 37257821 Free PMC article.

9

BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer's disease and related dementias.

Yin T, D'Adamio L. Yin T, et al. bioRxiv [Preprint]. 2023 Jun 14:2023.06.14.544924. doi: 10.1101/2023.06.14.544924. bioRxiv. 2023. PMID: 37398330 Free PMC article. Preprint.

10

Beyond amyloid: altered gene function in neurodegenerative diseases.

Yesiltepe M, Yin T, D'Adamio L. Yesiltepe M, et al. Among authors: yin t. Aging (Albany NY). 2023 Sep 20;15(18):9235-9237. doi: 10.18632/aging.204717. Epub 2023 Sep 20. Aging (Albany NY). 2023. PMID: 37733660 Free PMC article. No abstract available.

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