Monoamine oxidase-A (MAO-A) low-expression variants and increased risk of Plasmodium vivax malaria relapses.
Puça MCSB, Rodrigues DF, Salazar YEAR, Louzada J, Fontes CJF, Daher A, Pereira DB, Fernandes Vieira JL, Carvalho LH, de Brito CFA, Gil JP, de Sousa TN.
Puça MCSB, et al.
J Antimicrob Chemother. 2024 Jun 13:dkae196. doi: 10.1093/jac/dkae196. Online ahead of print.
J Antimicrob Chemother. 2024.
PMID: 38870082
Accordingly, polymorphisms in primaquine-metabolizing enzymes can impact the treatment efficacy. This pioneering study explores the influence of monoamine oxidase-A (MAO-A) on primaquine metabolism and its impact on malaria relapses. ...
Accordingly, polymorphisms in primaquine-metabolizing enzymes can impact the treatment efficacy. This pioneering study explores the influenc …