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A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia.
van Tilburg MAL, Parisien M, Boles RG, Drury GL, Smith-Voudouris J, Verma V, Khoury S, Chabot-Doré AJ, Nackley AG, Smith SB, Whitehead WE, Zolnoun DA, Slade GD, Tchivileva I, Maixner W, Diatchenko L. van Tilburg MAL, et al. Among authors: smith sb, smith voudouris j. Pain. 2020 Dec;161(12):2860-2871. doi: 10.1097/j.pain.0000000000001996. Pain. 2020. PMID: 32658146 Free PMC article.
Pain perception is altered by a nucleotide polymorphism in SCN9A.
Reimann F, Cox JJ, Belfer I, Diatchenko L, Zaykin DV, McHale DP, Drenth JP, Dai F, Wheeler J, Sanders F, Wood L, Wu TX, Karppinen J, Nikolajsen L, Männikkö M, Max MB, Kiselycznyk C, Poddar M, Te Morsche RH, Smith S, Gibson D, Kelempisioti A, Maixner W, Gribble FM, Woods CG. Reimann F, et al. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5148-53. doi: 10.1073/pnas.0913181107. Epub 2010 Mar 8. Proc Natl Acad Sci U S A. 2010. PMID: 20212137 Free PMC article.
Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot study.
Tchivileva IE, Lim PF, Smith SB, Slade GD, Diatchenko L, McLean SA, Maixner W. Tchivileva IE, et al. Among authors: smith sb. Pharmacogenet Genomics. 2010 Apr;20(4):239-48. doi: 10.1097/FPC.0b013e328337f9ab. Pharmacogenet Genomics. 2010. PMID: 20216107 Free PMC article. Clinical Trial.
Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1.
Costigan M, Belfer I, Griffin RS, Dai F, Barrett LB, Coppola G, Wu T, Kiselycznyk C, Poddar M, Lu Y, Diatchenko L, Smith S, Cobos EJ, Zaykin D, Allchorne A, Gershon E, Livneh J, Shen PH, Nikolajsen L, Karppinen J, Männikkö M, Kelempisioti A, Goldman D, Maixner W, Geschwind DH, Max MB, Seltzer Z, Woolf CJ. Costigan M, et al. Brain. 2010 Sep;133(9):2519-27. doi: 10.1093/brain/awq195. Epub 2010 Aug 18. Brain. 2010. PMID: 20724292 Free PMC article.
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
Sorge RE, Trang T, Dorfman R, Smith SB, Beggs S, Ritchie J, Austin JS, Zaykin DV, Vander Meulen H, Costigan M, Herbert TA, Yarkoni-Abitbul M, Tichauer D, Livneh J, Gershon E, Zheng M, Tan K, John SL, Slade GD, Jordan J, Woolf CJ, Peltz G, Maixner W, Diatchenko L, Seltzer Z, Salter MW, Mogil JS. Sorge RE, et al. Among authors: smith sb. Nat Med. 2012 Mar 25;18(4):595-9. doi: 10.1038/nm.2710. Nat Med. 2012. PMID: 22447075 Free PMC article.
685 results