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Phase 1 study of ARQ 761, a β-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis.
Gerber DE, Beg MS, Fattah F, Frankel AE, Fatunde O, Arriaga Y, Dowell JE, Bisen A, Leff RD, Meek CC, Putnam WC, Kallem RR, Subramaniyan I, Dong Y, Bolluyt J, Sarode V, Luo X, Xie Y, Schwartz B, Boothman DA. Gerber DE, et al. Among authors: subramaniyan i. Br J Cancer. 2018 Oct;119(8):928-936. doi: 10.1038/s41416-018-0278-4. Epub 2018 Oct 15. Br J Cancer. 2018. PMID: 30318513 Free PMC article. Clinical Trial.
Concentration-dependent Early Antivascular and Antitumor Effects of Itraconazole in Non-Small Cell Lung Cancer.
Gerber DE, Putnam WC, Fattah FJ, Kernstine KH, Brekken RA, Pedrosa I, Skelton R, Saltarski JM, Lenkinski RE, Leff RD, Ahn C, Padmanabhan C, Chembukar V, Kasiri S, Kallem RR, Subramaniyan I, Yuan Q, Do QN, Xi Y, Reznik SI, Pelosof L, Faubert B, DeBerardinis RJ, Kim J. Gerber DE, et al. Among authors: subramaniyan i. Clin Cancer Res. 2020 Nov 15;26(22):6017-6027. doi: 10.1158/1078-0432.CCR-20-1916. Epub 2020 Aug 26. Clin Cancer Res. 2020. PMID: 32847935 Free PMC article. Clinical Trial.
Itraconazole Exerts Its Antitumor Effect in Esophageal Cancer By Suppressing the HER2/AKT Signaling Pathway.
Zhang W, Bhagwath AS, Ramzan Z, Williams TA, Subramaniyan I, Edpuganti V, Kallem RR, Dunbar KB, Ding P, Gong K, Geurkink SA, Beg MS, Kim J, Zhang Q, Habib AA, Choi SH, Lapsiwala R, Bhagwath G, Dowell JE, Melton SD, Jie C, Putnam WC, Pham TH, Wang DH. Zhang W, et al. Among authors: subramaniyan i. Mol Cancer Ther. 2021 Oct;20(10):1904-1915. doi: 10.1158/1535-7163.MCT-20-0638. Epub 2021 Aug 10. Mol Cancer Ther. 2021. PMID: 34376577 Free PMC article. Clinical Trial.
An implanted port-catheter system for repeated hepatic arterial infusion of low-density lipoprotein-docosahexaenoic acid nanoparticles in normal rats: A safety study.
Wang Y, Li J, Subramaniyan I, do Vale GD, Chaudhary J, Anwar A, Wight-Carter M, McDonald JG, Putnam WC, Qin T, Zhang H, Corbin IR. Wang Y, et al. Among authors: subramaniyan i. Toxicol Appl Pharmacol. 2020 Aug 1;400:115037. doi: 10.1016/j.taap.2020.115037. Epub 2020 May 15. Toxicol Appl Pharmacol. 2020. PMID: 32417438 Free PMC article.
Effect of Doxorubicin on Myocardial Bicarbonate Production From Pyruvate Dehydrogenase in Women With Breast Cancer.
Park JM, Reed GD, Liticker J, Putnam WC, Chandra A, Yaros K, Afzal A, MacNamara J, Raza J, Hall RG, Baxter J, Derner K, Pena S, Kallem RR, Subramaniyan I, Edpuganti V, Harrison CE, Muthukumar A, Lewis C, Reddy S, Unni N, Klemow D, Syed S, Li H, Cole S, Froehlich T, Ayers C, de Lemos J, Malloy CR, Haley B, Zaha VG. Park JM, et al. Among authors: subramaniyan i. Circ Res. 2020 Dec 4;127(12):1568-1570. doi: 10.1161/CIRCRESAHA.120.317970. Epub 2020 Oct 14. Circ Res. 2020. PMID: 33054563 Free PMC article. No abstract available.
Development and validation of a quantitative LC-MS/MS method for the simultaneous determination of ceftolozane and tazobactam in human plasma and urine.
Putnam WC, Kallem RR, Edpuganti V, Subramaniyan I, Hall RG 2nd. Putnam WC, et al. Among authors: subramaniyan i. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Nov 30;1159:122354. doi: 10.1016/j.jchromb.2020.122354. Epub 2020 Sep 2. J Chromatogr B Analyt Technol Biomed Life Sci. 2020. PMID: 32905989 Clinical Trial.