Suemizu H - Search Results

1

Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data.

Nakayama K, Kamimura H, Suemizu H, Yoneda N, Nishiwaki M, Iwamoto K, Mizunaga M, Negoro T, Ito S, Yamazaki H, Nomura Y. Nakayama K, et al. Among authors: suemizu h. Drug Metab Pharmacokinet. 2020 Aug;35(4):389-396. doi: 10.1016/j.dmpk.2020.05.004. Epub 2020 May 20. Drug Metab Pharmacokinet. 2020. PMID: 32690433

2

In vivo formation of a glutathione conjugate derived from thalidomide in humanized uPA-NOG mice.

Yamazaki H, Suemizu H, Igaya S, Shimizu M, Shibata N, Nakamura M, Chowdhury G, Guengerich FP. Yamazaki H, et al. Among authors: suemizu h. Chem Res Toxicol. 2011 Mar 21;24(3):287-9. doi: 10.1021/tx200005g. Epub 2011 Feb 7. Chem Res Toxicol. 2011. PMID: 21299192 Free PMC article.

3

In vivo formation of dihydroxylated and glutathione conjugate metabolites derived from thalidomide and 5-Hydroxythalidomide in humanized TK-NOG mice.

Yamazaki H, Suemizu H, Shimizu M, Igaya S, Shibata N, Nakamura M, Chowdhury G, Guengerich FP. Yamazaki H, et al. Among authors: suemizu h. Chem Res Toxicol. 2012 Feb 20;25(2):274-6. doi: 10.1021/tx300009j. Epub 2012 Jan 25. Chem Res Toxicol. 2012. PMID: 22268628 Free PMC article.

4

Plasma concentrations of melengestrol acetate in humans extrapolated from the pharmacokinetics established in in vivo experiments with rats and chimeric mice with humanized liver and physiologically based pharmacokinetic modeling.

Tsukada A, Suemizu H, Murayama N, Takano R, Shimizu M, Nakamura M, Yamazaki H. Tsukada A, et al. Among authors: suemizu h. Regul Toxicol Pharmacol. 2013 Apr;65(3):316-24. doi: 10.1016/j.yrtph.2013.01.008. Epub 2013 Feb 5. Regul Toxicol Pharmacol. 2013. PMID: 23395687

5

In vivo drug interactions of the teratogen thalidomide with midazolam: heterotropic cooperativity of human cytochrome P450 in humanized TK-NOG mice.

Yamazaki H, Suemizu H, Murayama N, Utoh M, Shibata N, Nakamura M, Guengerich FP. Yamazaki H, et al. Among authors: suemizu h. Chem Res Toxicol. 2013 Mar 18;26(3):486-9. doi: 10.1021/tx400008g. Epub 2013 Mar 1. Chem Res Toxicol. 2013. PMID: 23419139 Free PMC article.

6

The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice.

Higuchi Y, Kawai K, Yamazaki H, Nakamura M, Bree F, Guguen-Guillouzo C, Suemizu H. Higuchi Y, et al. Among authors: suemizu h. Xenobiotica. 2014 Jan;44(2):146-53. doi: 10.3109/00498254.2013.836257. Epub 2013 Sep 25. Xenobiotica. 2014. PMID: 24066694 Free PMC article.

7

Thalidomide increases human hepatic cytochrome P450 3A enzymes by direct activation of the pregnane X receptor.

Murayama N, van Beuningen R, Suemizu H, Guillouzo CG, Shibata N, Yajima K, Utoh M, Shimizu M, Chesné C, Nakamura M, Guengerich FP, Houtman R, Yamazaki H. Murayama N, et al. Among authors: suemizu h. Chem Res Toxicol. 2014 Feb 17;27(2):304-308. doi: 10.1021/tx4004374. Epub 2014 Feb 5. Chem Res Toxicol. 2014. PMID: 24460184 Free PMC article.

8

Human plasma concentrations of herbicidal carbamate molinate extrapolated from the pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and physiologically based pharmacokinetic modeling.

Yamashita M, Suemizu H, Murayama N, Nishiyama S, Shimizu M, Yamazaki H. Yamashita M, et al. Among authors: suemizu h. Regul Toxicol Pharmacol. 2014 Oct;70(1):214-21. doi: 10.1016/j.yrtph.2014.06.028. Epub 2014 Jul 10. Regul Toxicol Pharmacol. 2014. PMID: 25016177

9

Pharmacokinetics and effects on serum cholinesterase activities of organophosphorus pesticides acephate and chlorpyrifos in chimeric mice transplanted with human hepatocytes.

Suemizu H, Sota S, Kuronuma M, Shimizu M, Yamazaki H. Suemizu H, et al. Regul Toxicol Pharmacol. 2014 Nov;70(2):468-73. doi: 10.1016/j.yrtph.2014.08.010. Epub 2014 Aug 23. Regul Toxicol Pharmacol. 2014. PMID: 25158275

10

Formation of the accumulative human metabolite and human-specific glutathione conjugate of diclofenac in TK-NOG chimeric mice with humanized livers.

Kamimura H, Ito S, Nozawa K, Nakamura S, Chijiwa H, Nagatsuka S, Kuronuma M, Ohnishi Y, Suemizu H, Ninomiya S. Kamimura H, et al. Among authors: suemizu h. Drug Metab Dispos. 2015 Mar;43(3):309-16. doi: 10.1124/dmd.114.061689. Epub 2014 Dec 11. Drug Metab Dispos. 2015. PMID: 25504502

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

197 results

Search Page