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The p.P1127S pathogenic variant lowers von Willebrand factor levels through higher affinity for the macrophagic scavenger receptor LRP1: Clinical phenotype and pathogenic mechanisms.
Sacco M, Lancellotti S, Branchini A, Tardugno M, Testa MF, Lunghi B, Bernardi F, Pinotti M, Giusti B, Castaman G, De Cristofaro R. Sacco M, et al. Among authors: tardugno m. J Thromb Haemost. 2022 Aug;20(8):1818-1829. doi: 10.1111/jth.15765. Epub 2022 Jun 9. J Thromb Haemost. 2022. PMID: 35596664 Free PMC article.
ADAMTS-13/von Willebrand factor ratio: A prognostic biomarker for portal vein thrombosis in compensated cirrhosis. A prospective observational study.
Sacco M, Tardugno M, Lancellotti S, Ferretti A, Ponziani FR, Riccardi L, Zocco MA, De Magistris A, Santopaolo F, Pompili M, De Cristofaro R. Sacco M, et al. Among authors: tardugno m. Dig Liver Dis. 2022 Dec;54(12):1672-1680. doi: 10.1016/j.dld.2022.06.004. Epub 2022 Jun 29. Dig Liver Dis. 2022. PMID: 35778228
Low ADAMTS-13/VWF ratio and altered gut-liver axis predict complications of advanced chronic liver disease: a pilot study.
Ponziani FR, Sacco M, Tardugno M, Santopaolo F, Marsico A, Manna S, Lancellotti S, Gasbarrini A, De Cristofaro R, Pompili M. Ponziani FR, et al. Among authors: tardugno m. Gastroenterol Rep (Oxf). 2022 Nov 7;10:goac065. doi: 10.1093/gastro/goac065. eCollection 2022. Gastroenterol Rep (Oxf). 2022. PMID: 36381222 Free PMC article. No abstract available.
1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells.
Valente S, Mellini P, Spallotta F, Carafa V, Nebbioso A, Polletta L, Carnevale I, Saladini S, Trisciuoglio D, Gabellini C, Tardugno M, Zwergel C, Cencioni C, Atlante S, Moniot S, Steegborn C, Budriesi R, Tafani M, Del Bufalo D, Altucci L, Gaetano C, Mai A. Valente S, et al. Among authors: tardugno m. J Med Chem. 2016 Feb 25;59(4):1471-91. doi: 10.1021/acs.jmedchem.5b01117. Epub 2016 Jan 5. J Med Chem. 2016. PMID: 26689352
Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.
Valente S, Liu Y, Schnekenburger M, Zwergel C, Cosconati S, Gros C, Tardugno M, Labella D, Florean C, Minden S, Hashimoto H, Chang Y, Zhang X, Kirsch G, Novellino E, Arimondo PB, Miele E, Ferretti E, Gulino A, Diederich M, Cheng X, Mai A. Valente S, et al. Among authors: tardugno m. J Med Chem. 2014 Feb 13;57(3):701-13. doi: 10.1021/jm4012627. Epub 2014 Jan 15. J Med Chem. 2014. PMID: 24387159 Free PMC article.
Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase.
Tortorici M, Borrello MT, Tardugno M, Chiarelli LR, Pilotto S, Ciossani G, Vellore NA, Bailey SG, Cowan J, O'Connell M, Crabb SJ, Packham G, Mai A, Baron R, Ganesan A, Mattevi A. Tortorici M, et al. Among authors: tardugno m. ACS Chem Biol. 2013 Aug 16;8(8):1677-82. doi: 10.1021/cb4001926. Epub 2013 Jun 11. ACS Chem Biol. 2013. PMID: 23721412
tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells.
Valente S, Trisciuoglio D, Tardugno M, Benedetti R, Labella D, Secci D, Mercurio C, Boggio R, Tomassi S, Di Maro S, Novellino E, Altucci L, Del Bufalo D, Mai A, Cosconati S. Valente S, et al. Among authors: tardugno m. ChemMedChem. 2013 May;8(5):800-11. doi: 10.1002/cmdc.201300005. Epub 2013 Mar 25. ChemMedChem. 2013. PMID: 23526814
17 results