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Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.
Zhang J, Mullighan CG, Harvey RC, Wu G, Chen X, Edmonson M, Buetow KH, Carroll WL, Chen IM, Devidas M, Gerhard DS, Loh ML, Reaman GH, Relling MV, Camitta BM, Bowman WP, Smith MA, Willman CL, Downing JR, Hunger SP. Zhang J, et al. Among authors: mullighan cg. Blood. 2011 Sep 15;118(11):3080-7. doi: 10.1182/blood-2011-03-341412. Epub 2011 Jun 16. Blood. 2011. PMID: 21680795 Free PMC article.
Genome sequencing of lymphoid malignancies.
Mullighan CG. Mullighan CG. Blood. 2013 Dec 5;122(24):3899-907. doi: 10.1182/blood-2013-08-460311. Epub 2013 Sep 16. Blood. 2013. PMID: 24041576 Free article. Review.
Therapy of pediatric ALL: from Bowie to Obama.
Mullighan CG, Hunger SP. Mullighan CG, et al. Blood. 2013 Oct 10;122(15):2531-2. doi: 10.1182/blood-2013-09-523688. Blood. 2013. PMID: 24113793 Free article. No abstract available.
A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults.
Perez-Andreu V, Roberts KG, Xu H, Smith C, Zhang H, Yang W, Harvey RC, Payne-Turner D, Devidas M, Cheng IM, Carroll WL, Heerema NA, Carroll AJ, Raetz EA, Gastier-Foster JM, Marcucci G, Bloomfield CD, Mrózek K, Kohlschmidt J, Stock W, Kornblau SM, Konopleva M, Paietta E, Rowe JM, Luger SM, Tallman MS, Dean M, Burchard EG, Torgerson DG, Yue F, Wang Y, Pui CH, Jeha S, Relling MV, Evans WE, Gerhard DS, Loh ML, Willman CL, Hunger SP, Mullighan CG, Yang JJ. Perez-Andreu V, et al. Among authors: mullighan cg. Blood. 2015 Jan 22;125(4):680-6. doi: 10.1182/blood-2014-09-595744. Epub 2014 Dec 2. Blood. 2015. PMID: 25468567 Free PMC article. Clinical Trial.
Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia.
Maude SL, Dolai S, Delgado-Martin C, Vincent T, Robbins A, Selvanathan A, Ryan T, Hall J, Wood AC, Tasian SK, Hunger SP, Loh ML, Mullighan CG, Wood BL, Hermiston ML, Grupp SA, Lock RB, Teachey DT. Maude SL, et al. Among authors: mullighan cg. Blood. 2015 Mar 12;125(11):1759-67. doi: 10.1182/blood-2014-06-580480. Epub 2015 Feb 2. Blood. 2015. PMID: 25645356 Free PMC article.
PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia.
Dang J, Wei L, de Ridder J, Su X, Rust AG, Roberts KG, Payne-Turner D, Cheng J, Ma J, Qu C, Wu G, Song G, Huether RG, Schulman B, Janke L, Zhang J, Downing JR, van der Weyden L, Adams DJ, Mullighan CG. Dang J, et al. Among authors: mullighan cg. Blood. 2015 Jun 4;125(23):3609-17. doi: 10.1182/blood-2015-02-626127. Epub 2015 Apr 8. Blood. 2015. PMID: 25855603 Free PMC article.
Genome-wide analysis links NFATC2 with asparaginase hypersensitivity.
Fernandez CA, Smith C, Yang W, Mullighan CG, Qu C, Larsen E, Bowman WP, Liu C, Ramsey LB, Chang T, Karol SE, Loh ML, Raetz EA, Winick NJ, Hunger SP, Carroll WL, Jeha S, Pui CH, Evans WE, Devidas M, Relling MV. Fernandez CA, et al. Among authors: mullighan cg. Blood. 2015 Jul 2;126(1):69-75. doi: 10.1182/blood-2015-02-628800. Epub 2015 May 18. Blood. 2015. PMID: 25987655 Free PMC article.
374 results