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Our Exciting Journey to ACT-451840.
Boss C, Wittlin S. Boss C, et al. Chimia (Aarau). 2021 Nov 24;75(11):916-922. doi: 10.2533/chimia.2021.916. Chimia (Aarau). 2021. PMID: 34798913 Free article.
Discovery of substituted lactams as novel dual orexin receptor antagonists. Synthesis, preliminary structure-activity relationship studies and efforts towards improved metabolic stability and pharmacokinetic properties. Part 1.
Sifferlen T, Boller A, Chardonneau A, Cottreel E, Hoecker J, Aissaoui H, Williams JT, Brotschi C, Heidmann B, Siegrist R, Gatfield J, Treiber A, Brisbare-Roch C, Jenck F, Boss C. Sifferlen T, et al. Among authors: boss c. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1201-8. doi: 10.1016/j.bmcl.2013.12.092. Epub 2013 Dec 30. Bioorg Med Chem Lett. 2014. PMID: 24447850
Recent trends in orexin research--2010 to 2015.
Boss C, Roch C. Boss C, et al. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2875-87. doi: 10.1016/j.bmcl.2015.05.012. Epub 2015 May 15. Bioorg Med Chem Lett. 2015. PMID: 26045032 Review.
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