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Inflammasome activation by Pseudomonas aeruginosa's ExlA pore-forming toxin is detrimental for the host.
Cell Microbiol. 2020 Nov;22(11):e13251. doi: 10.1111/cmi.13251. Epub 2020 Sep 6.
Cell Microbiol. 2020.
PMID: 32779854
ExlA Pore-Forming Toxin: Localization at the Bacterial Membrane, Regulation of Secretion by Cyclic-Di-GMP, and Detection In Vivo.
Deruelle V, Berry A, Bouillot S, Job V, Maillard AP, Elsen S, Huber P.
Deruelle V, et al.
Toxins (Basel). 2021 Sep 11;13(9):645. doi: 10.3390/toxins13090645.
Toxins (Basel). 2021.
PMID: 34564649
Free PMC article.
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The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis.
Deruelle V, Bouillot S, Job V, Taillebourg E, Fauvarque MO, Attrée I, Huber P.
Deruelle V, et al.
Nat Commun. 2021 Jun 29;12(1):4024. doi: 10.1038/s41467-021-24337-9.
Nat Commun. 2021.
PMID: 34188051
Free PMC article.
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Prevalence of ExoY Activity in Pseudomonas aeruginosa Reference Panel Strains and Impact on Cytotoxicity in Epithelial Cells.
Silistre H, Raoux-Barbot D, Mancinelli F, Sangouard F, Dupin A, Belyy A, Deruelle V, Renault L, Ladant D, Touqui L, Mechold U.
Silistre H, et al. Among authors: deruelle v.
Front Microbiol. 2021 Oct 4;12:666097. doi: 10.3389/fmicb.2021.666097. eCollection 2021.
Front Microbiol. 2021.
PMID: 34675890
Free PMC article.
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Bacterial Nucleotidyl Cyclases Activated by Calmodulin or Actin in Host Cells: Enzyme Specificities and Cytotoxicity Mechanisms Identified to Date.
Teixeira-Nunes M, Retailleau P, Comisso M, Deruelle V, Mechold U, Renault L.
Teixeira-Nunes M, et al. Among authors: deruelle v.
Int J Mol Sci. 2022 Jun 16;23(12):6743. doi: 10.3390/ijms23126743.
Int J Mol Sci. 2022.
PMID: 35743184
Free PMC article.
Review.
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