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Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+Aβ1-42 peptide in rat hippocampal neurons.
Elmazoglu Z, Rangel-López E, Medina-Campos ON, Pedraza-Chaverri J, Túnez I, Aschner M, Santamaría A, Karasu Ç. Elmazoglu Z, et al. Among authors: karasu c. Neurochem Int. 2020 Nov;140:104817. doi: 10.1016/j.neuint.2020.104817. Epub 2020 Aug 8. Neurochem Int. 2020. PMID: 32781098 Free PMC article.
The Pharmacological Inhibition of Fatty Acid Amide Hydrolase Prevents Excitotoxic Damage in the Rat Striatum: Possible Involvement of CB1 Receptors Regulation.
Aguilera-Portillo G, Rangel-López E, Villeda-Hernández J, Chavarría A, Castellanos P, Elmazoglu Z, Karasu Ç, Túnez I, Pedraza G, Königsberg M, Santamaría A. Aguilera-Portillo G, et al. Among authors: karasu c. Mol Neurobiol. 2019 Feb;56(2):844-856. doi: 10.1007/s12035-018-1129-2. Epub 2018 May 25. Mol Neurobiol. 2019. PMID: 29802570
Comparison of Efficacy and Safety of Two Tea Tree Oil-Based Formulations in Patients with Chronic Blepharitis: A Double-Blinded Randomized Clinical Trial.
Ergun SB, Saribas GS, Yarayici S, Elmazoglu Z, Cardak A, Ozogul C, Ilhan MN, Karasu C, Evren Kemer O. Ergun SB, et al. Among authors: karasu c. Ocul Immunol Inflamm. 2020 Aug 17;28(6):888-897. doi: 10.1080/09273948.2019.1644349. Epub 2019 Aug 20. Ocul Immunol Inflamm. 2020. PMID: 31429629 Clinical Trial.
Triglyceride-lowering effect of the aldose reductase inhibitor cemtirestat-another factor that may contribute to attenuation of symptoms of peripheral neuropathy in STZ-diabetic rats.
Prnova MS, Kovacikova L, Svik K, Bezek S, Elmazoğlu Z, Karasu C, Stefek M. Prnova MS, et al. Among authors: karasu c. Naunyn Schmiedebergs Arch Pharmacol. 2020 Apr;393(4):651-661. doi: 10.1007/s00210-019-01769-1. Epub 2019 Dec 5. Naunyn Schmiedebergs Arch Pharmacol. 2020. PMID: 31802170
General toxicity assessment of the novel aldose reductase inhibitor cemtirestat.
Prnová MŠ, Račková L, Kováčiková L, Balleková J, Viskupičová J, Micháliková S, Taşkoparan B, Elmazoğlu Z, Rižner TL, Karasu C, Banerjee S, Štefek M. Prnová MŠ, et al. Among authors: karasu c. Interdiscip Toxicol. 2019 Nov;12(3):120-128. doi: 10.2478/intox-2019-0014. Epub 2020 Feb 20. Interdiscip Toxicol. 2019. PMID: 32210700 Free PMC article.
Antioxidant Mechanisms in the Neuroprotective Action of Cemtirestat: Studies in Chemical Models, Liposomes and Rat Brain Cortical Slices.
Soltesova Prnova M, Medina-Campos ON, Pedraza-Chaverri J, Colín-González AL, Piedra-García F, Rangel-López E, Kovacikova L, Ceylan A, Karasu C, Santamaria A, Stefek M. Soltesova Prnova M, et al. Among authors: karasu c. Neuroscience. 2020 Sep 1;443:206-217. doi: 10.1016/j.neuroscience.2020.07.014. Epub 2020 Jul 16. Neuroscience. 2020. PMID: 32681927
104 results