Wang B - Search Results

1

Dimeric small molecule agonists of EphA2 receptor inhibit glioblastoma cell growth.

Orahoske CM, Li Y, Petty A, Salem FM, Hanna J, Zhang W, Su B, Wang B. Orahoske CM, et al. Among authors: wang b. Bioorg Med Chem. 2020 Sep 15;28(18):115656. doi: 10.1016/j.bmc.2020.115656. Epub 2020 Jul 25. Bioorg Med Chem. 2020. PMID: 32828423 Free PMC article.

2

EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt.

Miao H, Li DQ, Mukherjee A, Guo H, Petty A, Cutter J, Basilion JP, Sedor J, Wu J, Danielpour D, Sloan AE, Cohen ML, Wang B. Miao H, et al. Among authors: wang b. Cancer Cell. 2009 Jul 7;16(1):9-20. doi: 10.1016/j.ccr.2009.04.009. Cancer Cell. 2009. PMID: 19573808 Free PMC article.

3

A small molecule agonist of EphA2 receptor tyrosine kinase inhibits tumor cell migration in vitro and prostate cancer metastasis in vivo.

Petty A, Myshkin E, Qin H, Guo H, Miao H, Tochtrop GP, Hsieh JT, Page P, Liu L, Lindner DJ, Acharya C, MacKerell AD Jr, Ficker E, Song J, Wang B. Petty A, et al. Among authors: wang b. PLoS One. 2012;7(8):e42120. doi: 10.1371/journal.pone.0042120. Epub 2012 Aug 15. PLoS One. 2012. PMID: 22916121 Free PMC article.

4

EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.

Miao H, Gale NW, Guo H, Qian J, Petty A, Kaspar J, Murphy AJ, Valenzuela DM, Yancopoulos G, Hambardzumyan D, Lathia JD, Rich JN, Lee J, Wang B. Miao H, et al. Among authors: wang b. Oncogene. 2015 Jan 29;34(5):558-67. doi: 10.1038/onc.2013.590. Epub 2014 Feb 3. Oncogene. 2015. PMID: 24488013 Free PMC article.

5

Binding and function of phosphotyrosines of the Ephrin A2 (EphA2) receptor using synthetic sterile α motif (SAM) domains.

Borthakur S, Lee H, Kim S, Wang BC, Buck M. Borthakur S, et al. J Biol Chem. 2014 Jul 11;289(28):19694-703. doi: 10.1074/jbc.M114.567602. Epub 2014 May 13. J Biol Chem. 2014. PMID: 24825902 Free PMC article.

6

A role of the SAM domain in EphA2 receptor activation.

Shi X, Hapiak V, Zheng J, Muller-Greven J, Bowman D, Lingerak R, Buck M, Wang BC, Smith AW. Shi X, et al. Sci Rep. 2017 Mar 24;7:45084. doi: 10.1038/srep45084. Sci Rep. 2017. PMID: 28338017 Free PMC article.

7

Design and synthesis of small molecule agonists of EphA2 receptor.

Petty A, Idippily N, Bobba V, Geldenhuys WJ, Zhong B, Su B, Wang B. Petty A, et al. Among authors: wang b. Eur J Med Chem. 2018 Jan 1;143:1261-1276. doi: 10.1016/j.ejmech.2017.10.026. Epub 2017 Oct 10. Eur J Med Chem. 2018. PMID: 29128116 Free PMC article.

8

A quantitative LC-MS/MS method for determination of a small molecule agonist of EphA2 in mouse plasma and brain tissue.

Zhong B, Li Y, Idippily N, Petty A, Su B, Wang B. Zhong B, et al. Among authors: wang b. Biomed Chromatogr. 2019 Apr;33(4):e4461. doi: 10.1002/bmc.4461. Epub 2019 Jan 16. Biomed Chromatogr. 2019. PMID: 30548501 Free PMC article.

9

Small-Molecule HSP27 Inhibitor Abolishes Androgen Receptors in Glioblastoma.

Li Y, Orahoske CM, Geldenhuys WJ, Bhattarai A, Sabbagh A, Bobba V, Salem FM, Zhang W, Shukla GC, Lathia JD, Wang B, Su B. Li Y, et al. Among authors: wang b. J Med Chem. 2021 Feb 11;64(3):1570-1583. doi: 10.1021/acs.jmedchem.0c01537. Epub 2021 Feb 1. J Med Chem. 2021. PMID: 33523674 Free PMC article.

10

Pharmacokinetic and brain distribution study of an anti-glioblastoma agent in mice by HPLC-MS/MS.

Li Y, Dano R, Li C, Zhang W, Lathia JD, Wang B, Su B. Li Y, et al. Among authors: wang b. Biomed Chromatogr. 2022 Mar;36(3):e5310. doi: 10.1002/bmc.5310. Epub 2022 Jan 12. Biomed Chromatogr. 2022. PMID: 34981554 Free PMC article.

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