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Dopamine and Glutamate in Antipsychotic-Responsive Compared With Antipsychotic-Nonresponsive Psychosis: A Multicenter Positron Emission Tomography and Magnetic Resonance Spectroscopy Study (STRATA).
Egerton A, Murphy A, Donocik J, Anton A, Barker GJ, Collier T, Deakin B, Drake R, Eliasson E, Emsley R, Gregory CJ, Griffiths K, Kapur S, Kassoumeri L, Knight L, Lambe EJB, Lawrie SM, Lees J, Lewis S, Lythgoe DJ, Matthews J, McGuire P, McNamee L, Semple S, Shaw AD, Singh KD, Stockton-Powdrell C, Talbot PS, Veronese M, Wagner E, Walters JTR, Williams SR, MacCabe JH, Howes OD. Egerton A, et al. Among authors: murphy a. Schizophr Bull. 2021 Mar 16;47(2):505-516. doi: 10.1093/schbul/sbaa128. Schizophr Bull. 2021. PMID: 32910150 Free PMC article.
Acute naltrexone does not remediate fronto-striatal disturbances in alcoholic and alcoholic polysubstance-dependent populations during a monetary incentive delay task.
Nestor LJ, Murphy A, McGonigle J, Orban C, Reed L, Taylor E, Flechais R, Paterson LM, Smith D, Bullmore ET, Ersche KD, Suckling J, Tait R, Elliott R, Deakin B, Rabiner I, Lingford-Hughes A, Nutt DJ, Sahakian B, Robbins TW; ICCAM Consortium. Nestor LJ, et al. Among authors: murphy a. Addict Biol. 2017 Nov;22(6):1576-1589. doi: 10.1111/adb.12444. Epub 2016 Sep 6. Addict Biol. 2017. PMID: 27600363 Free article. Clinical Trial.
Naltrexone ameliorates functional network abnormalities in alcohol-dependent individuals.
Morris LS, Baek K, Tait R, Elliott R, Ersche KD, Flechais R, McGonigle J, Murphy A, Nestor LJ, Orban C, Passetti F, Paterson LM, Rabiner I, Reed L, Smith D, Suckling J, Taylor EM, Bullmore ET, Lingford-Hughes AR, Deakin B, Nutt DJ, Sahakian BJ, Robbins TW, Voon V; ICCAM Consortium. Morris LS, et al. Among authors: murphy a. Addict Biol. 2018 Jan;23(1):425-436. doi: 10.1111/adb.12503. Epub 2017 Feb 28. Addict Biol. 2018. PMID: 28247526 Free PMC article.
Naltrexone differentially modulates the neural correlates of motor impulse control in abstinent alcohol-dependent and polysubstance-dependent individuals.
Nestor LJ, Paterson LM, Murphy A, McGonigle J, Orban C, Reed L, Taylor E, Flechais R, Smith D, Bullmore ET, Ersche KD, Suckling J, Elliott R, Deakin B, Rabiner I, Lingford Hughes A, Sahakian BJ, Robbins TW, Nutt DJ; ICCAM Consortium. Nestor LJ, et al. Among authors: murphy a. Eur J Neurosci. 2019 Aug;50(3):2311-2321. doi: 10.1111/ejn.14262. Epub 2018 Nov 26. Eur J Neurosci. 2019. PMID: 30402987 Free PMC article. Clinical Trial.
Disturbances across whole brain networks during reward anticipation in an abstinent addiction population.
Nestor LJ, Suckling J, Ersche KD, Murphy A, McGonigle J, Orban C, Paterson LM, Reed L, Taylor E, Flechais R, Smith D, Bullmore ET, Elliott R, Deakin B, Rabiner I, Hughes AL, Sahakian BJ, Robbins TW, Nutt DJ; ICCAM Consortium. Nestor LJ, et al. Among authors: murphy a. Neuroimage Clin. 2020;27:102297. doi: 10.1016/j.nicl.2020.102297. Epub 2020 May 26. Neuroimage Clin. 2020. PMID: 32505119 Free PMC article.
Cross-sectional study comparing cognitive function in treatment responsive versus treatment non-responsive schizophrenia: evidence from the STRATA study.
Millgate E, Kravariti E, Egerton A, Howes OD, Murray RM, Kassoumeri L, Donocik J, Lewis S, Drake R, Lawrie S, Murphy A, Collier T, Lees J, Stockton-Powdrell C, Walters J, Deakin B, MacCabe J. Millgate E, et al. Among authors: murphy a. BMJ Open. 2021 Nov 25;11(11):e054160. doi: 10.1136/bmjopen-2021-054160. BMJ Open. 2021. PMID: 34824121 Free PMC article.
Impaired verbal memory function is related to anterior cingulate glutamate levels in schizophrenia: findings from the STRATA study.
Griffiths K, Egerton A, Millgate E, Anton A, Barker GJ, Deakin B, Drake R, Eliasson E, Gregory CJ, Howes OD, Kravariti E, Lawrie SM, Lewis S, Lythgoe DJ, Murphy A, McGuire P, Semple S, Stockton-Powdrell C, Walters JTR, Williams SR, MacCabe JH. Griffiths K, et al. Among authors: murphy a. Schizophrenia (Heidelb). 2022 Jul 12;8(1):60. doi: 10.1038/s41537-022-00265-5. Schizophrenia (Heidelb). 2022. PMID: 35853881 Free PMC article.
Selective D3 receptor antagonism modulates neural response during negative emotional processing in substance dependence.
Vamvakopoulou IA, Fonville L, Hayes A, McGonigle J, Elliott R, Ersche KD, Flechais R, Orban C, Murphy A, Smith DG, Suckling J, Taylor EM, Deakin B, Robbins TW, Nutt DJ, Lingford-Hughes AR, Paterson LM. Vamvakopoulou IA, et al. Among authors: murphy a. Front Psychiatry. 2022 Oct 19;13:998844. doi: 10.3389/fpsyt.2022.998844. eCollection 2022. Front Psychiatry. 2022. PMID: 36339857 Free PMC article.
Effects of naltrexone are influenced by childhood adversity during negative emotional processing in addiction recovery.
Savulich G, Riccelli R, Passamonti L, Correia M, Deakin JF, Elliott R, Flechais RS, Lingford-Hughes AR, McGonigle J, Murphy A, Nutt DJ, Orban C, Paterson LM, Reed LJ, Smith DG, Suckling J, Tait R, Taylor EM, Sahakian BJ, Robbins TW, Ersche KD. Savulich G, et al. Among authors: murphy a. Transl Psychiatry. 2017 Mar 7;7(3):e1054. doi: 10.1038/tp.2017.34. Transl Psychiatry. 2017. PMID: 28267152 Free PMC article. Clinical Trial.
3,691 results