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Gene targeting in the rat: advances and opportunities.
Jacob HJ, Lazar J, Dwinell MR, Moreno C, Geurts AM. Jacob HJ, et al. Among authors: dwinell mr. Trends Genet. 2010 Dec;26(12):510-8. doi: 10.1016/j.tig.2010.08.006. Epub 2010 Oct 1. Trends Genet. 2010. PMID: 20869786 Free PMC article. Review.
The emerging role for rat models in gene discovery.
Dwinell MR, Lazar J, Geurts AM. Dwinell MR, et al. Mamm Genome. 2011 Aug;22(7-8):466-75. doi: 10.1007/s00335-011-9346-2. Epub 2011 Jul 6. Mamm Genome. 2011. PMID: 21732192 Free PMC article. Review.
Identifying multiple causative genes at a single GWAS locus.
Flister MJ, Tsaih SW, O'Meara CC, Endres B, Hoffman MJ, Geurts AM, Dwinell MR, Lazar J, Jacob HJ, Moreno C. Flister MJ, et al. Among authors: dwinell mr. Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. Genome Res. 2013. PMID: 24006081 Free PMC article.
Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase.
Beyer AM, Raffai G, Weinberg BD, Fredrich K, Rodgers MS, Geurts AM, Jacob HJ, Dwinell MR, Lombard JH. Beyer AM, et al. Among authors: dwinell mr. Am J Physiol Heart Circ Physiol. 2014 Feb;306(3):H339-47. doi: 10.1152/ajpheart.00619.2012. Epub 2013 Dec 6. Am J Physiol Heart Circ Physiol. 2014. PMID: 24322611 Free PMC article.
2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research.
Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A; International Committee on Standardized Genetic Nomenclature for Mice; Rat Genome and Nomenclature Committee. Flister MJ, et al. J Cardiovasc Transl Res. 2015 Jun;8(4):269-77. doi: 10.1007/s12265-015-9626-4. Epub 2015 Apr 29. J Cardiovasc Transl Res. 2015. PMID: 25920443 Free PMC article. Review.
Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension.
Nayak S, Khan MA, Wan TC, Pei H, Linden J, Dwinell MR, Geurts AM, Imig JD, Auchampach JA. Nayak S, et al. Among authors: dwinell mr. Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. Purinergic Signal. 2015. PMID: 26385692 Free PMC article.
Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease.
Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M. Rubattu S, et al. Among authors: dwinell mr. J Am Heart Assoc. 2016 Feb 17;5(2):e002701. doi: 10.1161/JAHA.115.002701. J Am Heart Assoc. 2016. PMID: 26888427 Free PMC article.
106 results