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Linking amyloid protein aggregation and yeast survival.
Morell M, de Groot NS, Vendrell J, Avilés FX, Ventura S. Morell M, et al. Among authors: ventura s. Mol Biosyst. 2011 Apr;7(4):1121-8. doi: 10.1039/c0mb00297f. Epub 2011 Jan 14. Mol Biosyst. 2011. PMID: 21240401
The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity.
Chutna O, Gonçalves S, Villar-Piqué A, Guerreiro P, Marijanovic Z, Mendes T, Ramalho J, Emmanouilidou E, Ventura S, Klucken J, Barral DC, Giorgini F, Vekrellis K, Outeiro TF. Chutna O, et al. Among authors: ventura s. Hum Mol Genet. 2014 Dec 20;23(25):6732-45. doi: 10.1093/hmg/ddu391. Epub 2014 Aug 4. Hum Mol Genet. 2014. PMID: 25092884
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
Pujols J, Peña-Díaz S, Lázaro DF, Peccati F, Pinheiro F, González D, Carija A, Navarro S, Conde-Giménez M, García J, Guardiola S, Giralt E, Salvatella X, Sancho J, Sodupe M, Outeiro TF, Dalfó E, Ventura S. Pujols J, et al. Among authors: ventura s. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486. doi: 10.1073/pnas.1804198115. Epub 2018 Sep 24. Proc Natl Acad Sci U S A. 2018. PMID: 30249646 Free PMC article.
Chemical Chaperones as Novel Drugs for Parkinson's Disease.
Pujols J, Peña-Díaz S, Pallarès I, Ventura S. Pujols J, et al. Among authors: ventura s. Trends Mol Med. 2020 Apr;26(4):408-421. doi: 10.1016/j.molmed.2020.01.005. Epub 2020 Feb 12. Trends Mol Med. 2020. PMID: 32277934 Review.
921 results