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Mechanism-based modeling of the effect of a novel inhibitor of vascular adhesion protein-1 on albuminuria and renal function markers in patients with diabetic kidney disease.
Hoefman S, Snelder N, van Noort M, Garcia-Hernandez A, Onkels H, Larsson TE, Bergmann KR. Hoefman S, et al. Among authors: snelder n. J Pharmacokinet Pharmacodyn. 2021 Feb;48(1):21-38. doi: 10.1007/s10928-020-09716-x. Epub 2020 Sep 14. J Pharmacokinet Pharmacodyn. 2021. PMID: 32929612 Free PMC article.
Population Pharmacokinetic and Exposure-Response Analysis of Finerenone: Insights Based on Phase IIb Data and Simulations to Support Dose Selection for Pivotal Trials in Type 2 Diabetes with Chronic Kidney Disease.
Snelder N, Heinig R, Drenth HJ, Joseph A, Kolkhof P, Lippert J, Garmann D, Ploeger B, Eissing T. Snelder N, et al. Clin Pharmacokinet. 2020 Mar;59(3):359-370. doi: 10.1007/s40262-019-00820-x. Clin Pharmacokinet. 2020. PMID: 31583611 Free PMC article. Clinical Trial.
Pharmacokinetics and pharmacodynamics of finerenone in patients with chronic kidney disease and type 2 diabetes: Insights based on FIGARO-DKD and FIDELIO-DKD.
Eissing T, Goulooze SC, van den Berg P, van Noort M, Ruppert M, Snelder N, Garmann D, Lippert J, Heinig R, Brinker M, Heerspink HJL. Eissing T, et al. Among authors: snelder n. Diabetes Obes Metab. 2024 Mar;26(3):924-936. doi: 10.1111/dom.15387. Epub 2023 Nov 30. Diabetes Obes Metab. 2024. PMID: 38037539 Clinical Trial.
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