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The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells.
Lan X, Khandros E, Huang P, Peslak SA, Bhardwaj SK, Grevet JD, Abdulmalik O, Wang H, Keller CA, Giardine B, Baeza J, Duffner ER, El Demerdash O, Wu XS, Vakoc CR, Garcia BA, Hardison RC, Shi J, Blobel GA. Lan X, et al. Among authors: grevet jd. Blood Adv. 2019 May 28;3(10):1586-1597. doi: 10.1182/bloodadvances.2019032318. Blood Adv. 2019. PMID: 31126914 Free PMC article.
ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Lan X, Ren R, Feng R, Ly LC, Lan Y, Zhang Z, Aboreden N, Qin K, Horton JR, Grevet JD, Mayuranathan T, Abdulmalik O, Keller CA, Giardine B, Hardison RC, Crossley M, Weiss MJ, Cheng X, Shi J, Blobel GA. Lan X, et al. Among authors: grevet jd. Mol Cell. 2021 Jan 21;81(2):239-254.e8. doi: 10.1016/j.molcel.2020.11.006. Epub 2020 Dec 9. Mol Cell. 2021. PMID: 33301730 Free PMC article.
Keeping fetal hemoglobin in the loop.
Grevet JD, Blobel GA. Grevet JD, et al. Cell Cycle. 2014;13(20):3153-4. doi: 10.4161/15384101.2014.969995. Cell Cycle. 2014. PMID: 25485488 Free PMC article. No abstract available.