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HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation.
Blood Adv. 2020 Sep 22;4(18):4560-4572. doi: 10.1182/bloodadvances.2020002475.
Blood Adv. 2020.
PMID: 32956454
Free PMC article.
Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells.
Grevet JD, Lan X, Hamagami N, Edwards CR, Sankaranarayanan L, Ji X, Bhardwaj SK, Face CJ, Posocco DF, Abdulmalik O, Keller CA, Giardine B, Sidoli S, Garcia BA, Chou ST, Liebhaber SA, Hardison RC, Shi J, Blobel GA.
Grevet JD, et al.
Science. 2018 Jul 20;361(6399):285-290. doi: 10.1126/science.aao0932.
Science. 2018.
PMID: 30026227
Free PMC article.
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The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells.
Lan X, Khandros E, Huang P, Peslak SA, Bhardwaj SK, Grevet JD, Abdulmalik O, Wang H, Keller CA, Giardine B, Baeza J, Duffner ER, El Demerdash O, Wu XS, Vakoc CR, Garcia BA, Hardison RC, Shi J, Blobel GA.
Lan X, et al. Among authors: grevet jd.
Blood Adv. 2019 May 28;3(10):1586-1597. doi: 10.1182/bloodadvances.2019032318.
Blood Adv. 2019.
PMID: 31126914
Free PMC article.
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ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Lan X, Ren R, Feng R, Ly LC, Lan Y, Zhang Z, Aboreden N, Qin K, Horton JR, Grevet JD, Mayuranathan T, Abdulmalik O, Keller CA, Giardine B, Hardison RC, Crossley M, Weiss MJ, Cheng X, Shi J, Blobel GA.
Lan X, et al. Among authors: grevet jd.
Mol Cell. 2021 Jan 21;81(2):239-254.e8. doi: 10.1016/j.molcel.2020.11.006. Epub 2020 Dec 9.
Mol Cell. 2021.
PMID: 33301730
Free PMC article.
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Keeping fetal hemoglobin in the loop.
Grevet JD, Blobel GA.
Grevet JD, et al.
Cell Cycle. 2014;13(20):3153-4. doi: 10.4161/15384101.2014.969995.
Cell Cycle. 2014.
PMID: 25485488
Free PMC article.
No abstract available.
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Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.
Huang P, Keller CA, Giardine B, Grevet JD, Davies JOJ, Hughes JR, Kurita R, Nakamura Y, Hardison RC, Blobel GA.
Huang P, et al. Among authors: grevet jd.
Genes Dev. 2017 Aug 15;31(16):1704-1713. doi: 10.1101/gad.303461.117. Epub 2017 Sep 15.
Genes Dev. 2017.
PMID: 28916711
Free PMC article.
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Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins.
Siebert AP, Ma Z, Grevet JD, Demuro A, Parker I, Foskett JK.
Siebert AP, et al. Among authors: grevet jd.
J Biol Chem. 2013 Mar 1;288(9):6140-53. doi: 10.1074/jbc.M112.409789. Epub 2013 Jan 8.
J Biol Chem. 2013.
PMID: 23300080
Free PMC article.
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