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Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT, van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray B, Jacobson MP, Mühle E, Chesneau O, Fraser JS, Seiple IB. Li Q, et al. Among authors: seiple ib. Nature. 2020 Oct;586(7827):145-150. doi: 10.1038/s41586-020-2761-3. Epub 2020 Sep 23. Nature. 2020. PMID: 32968273 Free PMC article.
A platform for the discovery of new macrolide antibiotics.
Seiple IB, Zhang Z, Jakubec P, Langlois-Mercier A, Wright PM, Hog DT, Yabu K, Allu SR, Fukuzaki T, Carlsen PN, Kitamura Y, Zhou X, Condakes ML, Szczypiński FT, Green WD, Myers AG. Seiple IB, et al. Nature. 2016 May 19;533(7603):338-45. doi: 10.1038/nature17967. Nature. 2016. PMID: 27193679 Free PMC article.
A concise route to virginiamycin M2.
Li Q, Seiple IB. Li Q, et al. Among authors: seiple ib. Tetrahedron. 2019 Jun 14;75(24):3309-3318. doi: 10.1016/j.tet.2019.04.060. Epub 2019 May 1. Tetrahedron. 2019. PMID: 32764837 Free PMC article.
Modular synthesis of streptogramin antibiotics.
Li Q, Seiple IB. Li Q, et al. Among authors: seiple ib. Synlett. 2021 Apr;32(7):647-654. doi: 10.1055/a-1293-9655. Epub 2020 Oct 20. Synlett. 2021. PMID: 34113063 Free PMC article.
Label-retention expansion microscopy.
Shi X, Li Q, Dai Z, Tran AA, Feng S, Ramirez AD, Lin Z, Wang X, Chow TT, Chen J, Kumar D, McColloch AR, Reiter JF, Huang EJ, Seiple IB, Huang B. Shi X, et al. Among authors: seiple ib. J Cell Biol. 2021 Sep 6;220(9):e202105067. doi: 10.1083/jcb.202105067. Epub 2021 Jul 6. J Cell Biol. 2021. PMID: 34228783 Free PMC article.
Modular Approaches to Lankacidin Antibiotics.
Cai L, Yao Y, Yeon SK, Seiple IB. Cai L, et al. Among authors: seiple ib. J Am Chem Soc. 2020 Sep 2;142(35):15116-15126. doi: 10.1021/jacs.0c06648. Epub 2020 Aug 19. J Am Chem Soc. 2020. PMID: 32786797 Free PMC article.
37 results