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Mepolizumab treatment in patients with severe eosinophilic asthma.
Ortega HG, Liu MC, Pavord ID, Brusselle GG, FitzGerald JM, Chetta A, Humbert M, Katz LE, Keene ON, Yancey SW, Chanez P; MENSA Investigators. Ortega HG, et al. N Engl J Med. 2014 Sep 25;371(13):1198-207. doi: 10.1056/NEJMoa1403290. Epub 2014 Sep 8. N Engl J Med. 2014. PMID: 25199059 Free article. Clinical Trial.
Benralizumab for the Prevention of COPD Exacerbations.
Criner GJ, Celli BR, Brightling CE, Agusti A, Papi A, Singh D, Sin DD, Vogelmeier CF, Sciurba FC, Bafadhel M, Backer V, Kato M, Ramírez-Venegas A, Wei YF, Bjermer L, Shih VH, Jison M, O'Quinn S, Makulova N, Newbold P, Goldman M, Martin UJ; GALATHEA Study Investigators; TERRANOVA Study Investigators. Criner GJ, et al. N Engl J Med. 2019 Sep 12;381(11):1023-1034. doi: 10.1056/NEJMoa1905248. Epub 2019 May 20. N Engl J Med. 2019. PMID: 31112385 Clinical Trial.
Survey of Pharmaceutical Industry's Best Practices around In Vitro Transporter Assessment and Implications for Drug Development: Considerations from the International Consortium for Innovation and Quality for Pharmaceutical Development Transporter Working Group.
Rollison HE, Mitra P, Chanteux H, Fang Z, Liang X, Park SH, Costales C, Hanna I, Thakkar N, Vergis JM, Bow DAJ, Hillgren KM, Brumm J, Chu X, Hop CECA, Lai Y, Li CY, Mahar KM, Salphati L, Sane R, Shen H, Taskar K, Taub M, Tohyama K, Xu C, Fenner KS. Rollison HE, et al. Among authors: tohyama k. Drug Metab Dispos. 2024 Jun 17;52(7):582-596. doi: 10.1124/dmd.123.001587. Drug Metab Dispos. 2024. PMID: 38697852
Clinical impact and characteristics of erythroid dysplasia in adult aplastic anaemia: Results from a multicentre registry.
Maeda T, Matsuda A, Kanda J, Kawabata H, Ishikawa T, Tohyama K, Kitanaka A, Araseki K, Shimbo K, Hata T, Suzuki T, Kayano H, Usuki K, Shindo-Ueda M, Arima N, Nohgawa M, Ohta A, Chiba S, Miyazaki Y, Nakao S, Ozawa K, Arai S, Kurokawa M, Takaori-Kondo A, Mitani K; Japanese National Research Group on Idiopathic Bone Marrow Failure Syndromes. Maeda T, et al. Among authors: tohyama k. Br J Haematol. 2024 May;204(5):2086-2096. doi: 10.1111/bjh.19323. Epub 2024 Jan 31. Br J Haematol. 2024. PMID: 38296352
Discovery of a novel series of medium-sized cyclic enteropeptidase inhibitors.
Kikuchi F, Ikeda Z, Kakegawa K, Nishikawa Y, Sasaki S, Fukuda K, Takami K, Banno Y, Nishikawa H, Taya N, Nakahata T, Itono S, Yashiro H, Tsuchimori K, Hiyoshi H, Sasaki M, Tohyama K, Matsumiya K, Ishihara Y, Kawamoto T, Kamaura M, Watanabe M, Kitazaki T, Maekawa T, Sasaki M. Kikuchi F, et al. Among authors: tohyama k. Bioorg Med Chem. 2023 Oct 1;93:117462. doi: 10.1016/j.bmc.2023.117462. Epub 2023 Aug 29. Bioorg Med Chem. 2023. PMID: 37683572 Free article.
367 results