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Allergic sensitization impairs lung resident memory CD8 T-cell response and virus clearance.
Agrawal K, Ong LC, Monkley S, Thörn K, Israelsson E, Baturcam E, Rist C, Schön K, Blake S, Magnusson B, Cartwright J, Mitra S, Ravi A, Zounemat-Kermani N, Krishnaswamy JK, Lycke NY, Gehrmann U, Mattsson J; U-BIOPRED Study Group. Agrawal K, et al. Among authors: gehrmann u. J Allergy Clin Immunol. 2022 Dec;150(6):1415-1426.e9. doi: 10.1016/j.jaci.2022.07.004. Epub 2022 Jul 30. J Allergy Clin Immunol. 2022. PMID: 35917932
Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.
Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg MC, Picard C, Neven B, Fischer A, Amigorena S, Rieux-Laucat F, Manel N. Cerboni S, et al. Among authors: gehrmann u. J Exp Med. 2017 Jun 5;214(6):1769-1785. doi: 10.1084/jem.20161674. Epub 2017 May 8. J Exp Med. 2017. PMID: 28484079 Free PMC article.
A MALT1 inhibitor suppresses human myeloid DC, effector T-cell and B-cell responses and retains Th1/regulatory T-cell homeostasis.
Dumont C, Sivars U, Andreasson T, Odqvist L, Mattsson J, DeMicco A, Pardali K, Johansson G, Yrlid L, Cox RJ, Seeliger F, Larsson M, Gehrmann U, Davis AM, Vaarala O. Dumont C, et al. Among authors: gehrmann u. PLoS One. 2020 Sep 1;15(9):e0222548. doi: 10.1371/journal.pone.0222548. eCollection 2020. PLoS One. 2020. PMID: 32870913 Free PMC article.
Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.
Gehrmann U, Burbage M, Zueva E, Goudot C, Esnault C, Ye M, Carpier JM, Burgdorf N, Hoyler T, Suarez G, Joannas L, Heurtebise-Chrétien S, Durand S, Panes R, Bellemare-Pelletier A, Sáez PJ, Aprahamian F, Lefevre D, Adoue V, Zine El Aabidine A, Muhammad Ahmad M, Hivroz C, Joffre O, Cammas F, Kroemer G, Gagnon E, Andrau JC, Amigorena S. Gehrmann U, et al. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25839-25849. doi: 10.1073/pnas.1901639116. Epub 2019 Nov 27. Proc Natl Acad Sci U S A. 2019. PMID: 31776254 Free PMC article.
Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells.
Ding M, Malhotra R, Ottosson T, Lundqvist M, Mebrahtu A, Brengdahl J, Gehrmann U, Bäck E, Ross-Thriepland D, Isaksson I, Magnusson B, Sachsenmeier KF, Tegel H, Hober S, Uhlén M, Mayr LM, Davies R, Rockberg J, Schiavone LH. Ding M, et al. Among authors: gehrmann u. Sci Rep. 2021 Aug 18;11(1):16767. doi: 10.1038/s41598-021-96184-z. Sci Rep. 2021. PMID: 34408239 Free PMC article.
Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis during Chronic Obstructive Pulmonary Disease.
Naessens T, Morias Y, Hamrud E, Gehrmann U, Budida R, Mattsson J, Baker T, Skogberg G, Israelsson E, Thörn K, Schuijs MJ, Angermann B, Melville F, Staples KJ, Cunoosamy DM, Lambrecht BN. Naessens T, et al. Among authors: gehrmann u. Am J Respir Crit Care Med. 2020 Aug 15;202(4):535-548. doi: 10.1164/rccm.201906-1123OC. Am J Respir Crit Care Med. 2020. PMID: 32255375
34 results