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Adamantyl cannabinoids: a novel class of cannabinergic ligands.
Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, Hurst DP, Reggio PH, Deschamps JR, Parrish DA, George C, Järbe TU, Lamb RJ, Makriyannis A. Lu D, et al. Among authors: thakur ga. J Med Chem. 2005 Jul 14;48(14):4576-85. doi: 10.1021/jm058175c. J Med Chem. 2005. PMID: 15999995
Mass spectrometry-based proteomics of human cannabinoid receptor 2: covalent cysteine 6.47(257)-ligand interaction affording megagonist receptor activation.
Szymanski DW, Papanastasiou M, Melchior K, Zvonok N, Mercier RW, Janero DR, Thakur GA, Cha S, Wu B, Karger B, Makriyannis A. Szymanski DW, et al. Among authors: thakur ga. J Proteome Res. 2011 Oct 7;10(10):4789-98. doi: 10.1021/pr2005583. Epub 2011 Sep 13. J Proteome Res. 2011. PMID: 21861534 Free PMC article.
Novel adamantyl cannabinoids as CB1 receptor probes.
Thakur GA, Bajaj S, Paronis C, Peng Y, Bowman AL, Barak LS, Caron MG, Parrish D, Deschamps JR, Makriyannis A. Thakur GA, et al. J Med Chem. 2013 May 23;56(10):3904-21. doi: 10.1021/jm4000775. Epub 2013 May 14. J Med Chem. 2013. PMID: 23621789 Free PMC article.
Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): an allosteric agonist-positive allosteric modulator of α7 nicotinic acetylcholine receptors.
Thakur GA, Kulkarni AR, Deschamps JR, Papke RL. Thakur GA, et al. J Med Chem. 2013 Nov 14;56(21):8943-7. doi: 10.1021/jm401267t. Epub 2013 Oct 25. J Med Chem. 2013. PMID: 24090443 Free PMC article.
Controlled-deactivation cannabinergic ligands.
Sharma R, Nikas SP, Paronis CA, Wood JT, Halikhedkar A, Guo JJ, Thakur GA, Kulkarni S, Benchama O, Raghav JG, Gifford RS, Järbe TU, Bergman J, Makriyannis A. Sharma R, et al. Among authors: thakur ga. J Med Chem. 2013 Dec 27;56(24):10142-57. doi: 10.1021/jm4016075. Epub 2013 Dec 10. J Med Chem. 2013. PMID: 24286207 Free PMC article.
Probing the carboxyester side chain in controlled deactivation (-)-δ(8)-tetrahydrocannabinols.
Nikas SP, Sharma R, Paronis CA, Kulkarni S, Thakur GA, Hurst D, Wood JT, Gifford RS, Rajarshi G, Liu Y, Raghav JG, Guo JJ, Järbe TU, Reggio PH, Bergman J, Makriyannis A. Nikas SP, et al. Among authors: thakur ga. J Med Chem. 2015 Jan 22;58(2):665-81. doi: 10.1021/jm501165d. Epub 2014 Dec 16. J Med Chem. 2015. PMID: 25470070 Free PMC article.
134 results