Drag M - Search Results

1

SARS-CoV-2 M^pro inhibitors and activity-based probes for patient-sample imaging.

Rut W, Groborz K, Zhang L, Sun X, Zmudzinski M, Pawlik B, Wang X, Jochmans D, Neyts J, Młynarski W, Hilgenfeld R, Drag M. Rut W, et al. Among authors: drag m. Nat Chem Biol. 2021 Feb;17(2):222-228. doi: 10.1038/s41589-020-00689-z. Epub 2020 Oct 22. Nat Chem Biol. 2021. PMID: 33093684

2

Recent advances and concepts in substrate specificity determination of proteases using tailored libraries of fluorogenic substrates with unnatural amino acids.

Rut W, Kasperkiewicz P, Byzia A, Poreba M, Groborz K, Drag M. Rut W, et al. Among authors: drag m. Biol Chem. 2015 Apr;396(4):329-37. doi: 10.1515/hsz-2014-0315. Biol Chem. 2015. PMID: 25719315 Review.

3

SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme.

Békés M, Rut W, Kasperkiewicz P, Mulder MP, Ovaa H, Drag M, Lima CD, Huang TT. Békés M, et al. Among authors: drag m. Biochem J. 2015 Jun 1;468(2):215-26. doi: 10.1042/BJ20141170. Biochem J. 2015. PMID: 25764917 Free PMC article.

4

Design and Synthesis of Activity-Based Probes and Inhibitors for Bleomycin Hydrolase.

van der Linden WA, Segal E, Child MA, Byzia A, Drąg M, Bogyo M. van der Linden WA, et al. Among authors: drag m. Chem Biol. 2015 Aug 20;22(8):995-1001. doi: 10.1016/j.chembiol.2015.07.010. Epub 2015 Aug 6. Chem Biol. 2015. PMID: 26256478 Free PMC article.

5

Small Molecule Active Site Directed Tools for Studying Human Caspases.

Poreba M, Szalek A, Kasperkiewicz P, Rut W, Salvesen GS, Drag M. Poreba M, et al. Among authors: drag m. Chem Rev. 2015 Nov 25;115(22):12546-629. doi: 10.1021/acs.chemrev.5b00434. Epub 2015 Nov 9. Chem Rev. 2015. PMID: 26551511 Free PMC article. Review.

6

Structural basis for substrate specificity of Helicobacter pylori M17 aminopeptidase.

Modak JK, Rut W, Wijeyewickrema LC, Pike RN, Drag M, Roujeinikova A. Modak JK, et al. Among authors: drag m. Biochimie. 2016 Feb;121:60-71. doi: 10.1016/j.biochi.2015.11.021. Epub 2015 Dec 1. Biochimie. 2016. PMID: 26616008

7

Human 20S proteasome activity towards fluorogenic peptides of various chain lengths.

Rut W, Drag M. Rut W, et al. Among authors: drag m. Biol Chem. 2016 Sep 1;397(9):921-6. doi: 10.1515/hsz-2016-0176. Biol Chem. 2016. PMID: 27176742

8

Structure and substrate fingerprint of aminopeptidase P from Plasmodium falciparum.

Drinkwater N, Sivaraman KK, Bamert RS, Rut W, Mohamed K, Vinh NB, Scammells PJ, Drag M, McGowan S. Drinkwater N, et al. Among authors: drag m. Biochem J. 2016 Oct 1;473(19):3189-204. doi: 10.1042/BCJ20160550. Epub 2016 Jul 26. Biochem J. 2016. PMID: 27462122

9

Counter Selection Substrate Library Strategy for Developing Specific Protease Substrates and Probes.

Poreba M, Solberg R, Rut W, Lunde NN, Kasperkiewicz P, Snipas SJ, Mihelic M, Turk D, Turk B, Salvesen GS, Drag M. Poreba M, et al. Among authors: drag m. Cell Chem Biol. 2016 Aug 18;23(8):1023-35. doi: 10.1016/j.chembiol.2016.05.020. Epub 2016 Jul 28. Cell Chem Biol. 2016. PMID: 27478158 Free PMC article.

10

Extended substrate specificity and first potent irreversible inhibitor/activity-based probe design for Zika virus NS2B-NS3 protease.

Rut W, Zhang L, Kasperkiewicz P, Poreba M, Hilgenfeld R, Drąg M. Rut W, et al. Among authors: drag m. Antiviral Res. 2017 Mar;139:88-94. doi: 10.1016/j.antiviral.2016.12.018. Epub 2016 Dec 26. Antiviral Res. 2017. PMID: 28034744

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