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A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation?
Rakipovski G, Rolin B, Barascuk N, Lund HE, Bjørn Bonde MF, Djordjevic D, Wulff-Larsen PG, Petersen M, Kirk RK, Hultman K, Manfe V, Blume N, Zahn S, Lengquist M, Maegdefessel L, Hovingh GK, Conde-Knape K, Hedin U, Matic L, Nyberg M. Rakipovski G, et al. Among authors: kirk rk. Atherosclerosis. 2020 Dec;314:1-9. doi: 10.1016/j.atherosclerosis.2020.10.001. Epub 2020 Oct 6. Atherosclerosis. 2020. PMID: 33129080
Modulating the Gut Microbiota Improves Glucose Tolerance, Lipoprotein Profile and Atherosclerotic Plaque Development in ApoE-Deficient Mice.
Rune I, Rolin B, Larsen C, Nielsen DS, Kanter JE, Bornfeldt KE, Lykkesfeldt J, Buschard K, Kirk RK, Christoffersen B, Fels JJ, Josefsen K, Kihl P, Hansen AK. Rune I, et al. Among authors: kirk rk. PLoS One. 2016 Jan 22;11(1):e0146439. doi: 10.1371/journal.pone.0146439. eCollection 2016. PLoS One. 2016. PMID: 26799618 Free PMC article.
18F-FDG PET/MR-imaging in a Göttingen Minipig model of atherosclerosis: Correlations with histology and quantitative gene expression.
Ludvigsen TP, Pedersen SF, Vegge A, Ripa RS, Johannesen HH, Hansen AE, Löfgren J, Schumacher-Petersen C, Kirk RK, Pedersen HD, Christoffersen BØ, Ørbæk M, Forman JL, Klausen TL, Olsen LH, Kjaer A. Ludvigsen TP, et al. Among authors: kirk rk. Atherosclerosis. 2019 Jun;285:55-63. doi: 10.1016/j.atherosclerosis.2019.04.209. Epub 2019 Apr 9. Atherosclerosis. 2019. PMID: 31004968
Semaglutide treatment attenuates vessel remodelling in ApoE-/- mice following vascular injury and blood flow perturbation.
Jensen DM, Skovsted GF, Bonde MFB, Bentzon JF, Rolin B, Franck G, Ougaard MKE, Voetmann LM, Bachmann JC, Uryga A, Pyke C, Kirk RK, Hvid H, Knudsen LB, Lykkesfeldt J, Nyberg M. Jensen DM, et al. Among authors: kirk rk. Atheroscler Plus. 2022 Jun 4;49:32-41. doi: 10.1016/j.athplu.2022.05.004. eCollection 2022 Aug. Atheroscler Plus. 2022. PMID: 36644202 Free PMC article.
Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals.
Ludvigsen TP, Kirk RK, Christoffersen BØ, Pedersen HD, Martinussen T, Kildegaard J, Heegaard PM, Lykkesfeldt J, Olsen LH. Ludvigsen TP, et al. Among authors: kirk rk. J Transl Med. 2015 Sep 22;13:312. doi: 10.1186/s12967-015-0670-2. J Transl Med. 2015. PMID: 26394837 Free PMC article.
29 results