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Genome-wide detection of DNA double-strand breaks by in-suspension BLISS.
Nat Protoc. 2020 Dec;15(12):3894-3941. doi: 10.1038/s41596-020-0397-2. Epub 2020 Nov 2.
Nat Protoc. 2020.
PMID: 33139954
Dynamics of Double-Strand Breaks: Implications for the Formation of Chromosome Translocations.
Gothe HJ, Minneker V, Roukos V.
Gothe HJ, et al.
Adv Exp Med Biol. 2018;1044:27-38. doi: 10.1007/978-981-13-0593-1_3.
Adv Exp Med Biol. 2018.
PMID: 29956289
Review.
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Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.
Gothe HJ, Bouwman BAM, Gusmao EG, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A, Crosetto N, Roukos V.
Gothe HJ, et al.
Mol Cell. 2019 Jul 25;75(2):267-283.e12. doi: 10.1016/j.molcel.2019.05.015. Epub 2019 Jun 12.
Mol Cell. 2019.
PMID: 31202576
Free article.
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RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis.
Zhang S, Übelmesser N, Josipovic N, Forte G, Slotman JA, Chiang M, Gothe HJ, Gusmao EG, Becker C, Altmüller J, Houtsmuller AB, Roukos V, Wendt KS, Marenduzzo D, Papantonis A.
Zhang S, et al. Among authors: gothe hj.
Sci Adv. 2021 Oct 22;7(43):eabg8205. doi: 10.1126/sciadv.abg8205. Epub 2021 Oct 22.
Sci Adv. 2021.
PMID: 34678064
Free PMC article.
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HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types.
Zirkel A, Nikolic M, Sofiadis K, Mallm JP, Brackley CA, Gothe H, Drechsel O, Becker C, Altmüller J, Josipovic N, Georgomanolis T, Brant L, Franzen J, Koker M, Gusmao EG, Costa IG, Ullrich RT, Wagner W, Roukos V, Nürnberg P, Marenduzzo D, Rippe K, Papantonis A.
Zirkel A, et al.
Mol Cell. 2018 May 17;70(4):730-744.e6. doi: 10.1016/j.molcel.2018.03.030. Epub 2018 Apr 26.
Mol Cell. 2018.
PMID: 29706538
Free article.
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Operons are a conserved feature of nematode genomes.
Pettitt J, Philippe L, Sarkar D, Johnston C, Gothe HJ, Massie D, Connolly B, Müller B.
Pettitt J, et al. Among authors: gothe hj.
Genetics. 2014 Aug;197(4):1201-11. doi: 10.1534/genetics.114.162875. Epub 2014 Jun 14.
Genetics. 2014.
PMID: 24931407
Free PMC article.
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