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Synthesis of C,N'-linked bis-heterocycles using a deprotometalation-iodination-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells.
Hedidi M, Bentabed-Ababsa G, Derdour A, Roisnel T, Dorcet V, Chevallier F, Picot L, Thiéry V, Mongin F. Hedidi M, et al. Among authors: roisnel t. Bioorg Med Chem. 2014 Jul 1;22(13):3498-507. doi: 10.1016/j.bmc.2014.04.028. Epub 2014 Apr 24. Bioorg Med Chem. 2014. PMID: 24831678 Free article.
Deprotometalation-iodolysis and computed CH acidity of 1,2,3- and 1,2,4-triazoles. Application to the synthesis of resveratrol analogues.
Nagaradja E, Bentabed-Ababsa G, Scalabrini M, Chevallier F, Philippot S, Fontanay S, Duval RE, Halauko YS, Ivashkevich OA, Matulis VE, Roisnel T, Mongin F. Nagaradja E, et al. Among authors: roisnel t. Bioorg Med Chem. 2015 Oct 1;23(19):6355-63. doi: 10.1016/j.bmc.2015.08.031. Epub 2015 Aug 28. Bioorg Med Chem. 2015. PMID: 26344592
Structure elucidation {spectroscopic, single crystal X-ray diffraction and computational DFT studies} of new tailored benzenesulfonamide derived Schiff base copper(II) intercalating complexes: Comprehensive biological profile {DNA binding, pBR322 DNA cleavage, Topo I inhibition and cytotoxic activity}.
Afsan Z, Roisnel T, Tabassum S, Arjmand F. Afsan Z, et al. Among authors: roisnel t. Bioorg Chem. 2020 Jan;94:103427. doi: 10.1016/j.bioorg.2019.103427. Epub 2019 Nov 9. Bioorg Chem. 2020. PMID: 31735357
Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase.
Brahmaiah D, Kanaka Durga Bhavani A, Aparna P, Sampath Kumar N, Solhi H, Le Guevel R, Baratte B, Ruchaud S, Bach S, Singh Jadav S, Raji Reddy C, Roisnel T, Mosset P, Levoin N, Grée R. Brahmaiah D, et al. Among authors: roisnel t. Bioorg Med Chem. 2021 Feb 1;31:115962. doi: 10.1016/j.bmc.2020.115962. Epub 2020 Dec 31. Bioorg Med Chem. 2021. PMID: 33422908
Deproto-metallation and computed CH acidity of 2-aryl-1,2,3-triazoles.
Chevallier F, Blin T, Nagaradja E, Lassagne F, Roisnel T, Halauko YS, Matulis VE, Ivashkevich OA, Mongin F. Chevallier F, et al. Among authors: roisnel t. Org Biomol Chem. 2012 Jul 7;10(25):4878-85. doi: 10.1039/c2ob25554e. Epub 2012 May 21. Org Biomol Chem. 2012. PMID: 22610262 Free article.
379 results