Orr D - Search Results

1

Restoring carbapenem efficacy: a novel carbapenem companion targeting metallo-β-lactamases in carbapenem-resistant Enterobacterales.

Ooi N, Lee VE, Chalam-Judge N, Newman R, Wilkinson AJ, Cooper IR, Orr D, Lee S, Savage VJ. Ooi N, et al. Among authors: orr d. J Antimicrob Chemother. 2021 Jan 19;76(2):460-466. doi: 10.1093/jac/dkaa455. J Antimicrob Chemother. 2021. PMID: 33152764 Free PMC article.

2

Discovery and structure-activity relationships of a novel oxazolidinone class of bacterial type II topoisomerase inhibitors.

Lyons A, Kirkham J, Blades K, Orr D, Dauncey E, Smith O, Dick E, Walker R, Matthews T, Bunt A, Finlayson J, Morrison I, Savage VJ, Moyo E, Butler HS, Newman R, Ooi N, Smith A, Charrier C, Ratcliffe AJ, Stokes NR, Best S, Salisbury AM, Craighead M, Cooper IR. Lyons A, et al. Among authors: orr d. Bioorg Med Chem Lett. 2022 Jun 1;65:128648. doi: 10.1016/j.bmcl.2022.128648. Epub 2022 Feb 26. Bioorg Med Chem Lett. 2022. PMID: 35231579

3

Incidence and epidemiology of levofloxacin resistance in Streptococcus pneumoniae: experience from a tertiary referral hospital in England.

Orr D, Wilkinson P, Moyce L, Martin S, George R, Pichon B. Orr D, et al. J Antimicrob Chemother. 2010 Mar;65(3):449-52. doi: 10.1093/jac/dkp463. Epub 2009 Dec 17. J Antimicrob Chemother. 2010. PMID: 20019170

4

Penicillin-binding proteins of Pseudomonas aeruginosa. Comparison of two strains differing in their resistance to beta-lactam antibiotics.

Curtis NA, Orr D, Boulton MG, Ross GW. Curtis NA, et al. Among authors: orr d. J Antimicrob Chemother. 1981 Feb;7(2):127-36. doi: 10.1093/jac/7.2.127. J Antimicrob Chemother. 1981. PMID: 6783607 No abstract available.

5

Seroprevalence of SARS-CoV-2 infection in healthcare workers in a large teaching hospital in the North West of England: a period prevalence survey.

Shorten RJ, Haslam S, Hurley MA, Rowbottom A, Myers M, Wilkinson P, Orr D. Shorten RJ, et al. Among authors: orr d. BMJ Open. 2021 Mar 16;11(3):e045384. doi: 10.1136/bmjopen-2020-045384. BMJ Open. 2021. PMID: 33727275 Free PMC article.

6

Synthesis and structure-activity relationships of a series of penicillin-derived HIV proteinase inhibitors containing a stereochemically unique peptide isostere.

Holmes DS, Bethell RC, Cammack N, Clemens IR, Kitchin J, McMeekin P, Mo CL, Orr DC, Patel B, Paternoster IL, et al. Holmes DS, et al. Among authors: orr dc. J Med Chem. 1993 Oct 15;36(21):3129-36. doi: 10.1021/jm00073a012. J Med Chem. 1993. PMID: 8230099

7

A series of penicillin derived C2-symmetric inhibitors of HIV-1 proteinase: synthesis, mode of interaction, and structure-activity relationships.

Humber DC, Bamford MJ, Bethell RC, Cammack N, Cobley K, Evans DN, Gray NM, Hann MM, Orr DC, Saunders J, et al. Humber DC, et al. Among authors: orr dc. J Med Chem. 1993 Oct 15;36(21):3120-8. doi: 10.1021/jm00073a011. J Med Chem. 1993. PMID: 8230098

8

Competition of beta-lactam antibiotics for the penicillin-binding proteins of Pseudomonas aeruginosa, Enterobacter cloacae, Klebsiella aerogenes, Proteus rettgeri, and Escherichia coli: comparison with antibacterial activity and effects upon bacterial morphology.

Curtis NA, Orr D, Ross GW, Boulton MG. Curtis NA, et al. Among authors: orr d. Antimicrob Agents Chemother. 1979 Sep;16(3):325-8. doi: 10.1128/AAC.16.3.325. Antimicrob Agents Chemother. 1979. PMID: 116592 Free PMC article.

9

The competition of alpha-sulfocephalosporins for the penicillin-binding proteins of Escherichia coli K12 and Pseudomonas aeruginosa--comparison with effects upon morphology.

Curtis NA, Boulton MG, Orr D, Ross GW. Curtis NA, et al. Among authors: orr d. J Antimicrob Chemother. 1980 Mar;6(2):189-96. doi: 10.1093/jac/6.2.189. J Antimicrob Chemother. 1980. PMID: 6769894 No abstract available.

10

The action of some beta-lactam antibiotics on the penicillin-binding proteins of Gram-negative bacteria.

Curtis NA, Orr DC, Boulton MG. Curtis NA, et al. Among authors: orr dc. Philos Trans R Soc Lond B Biol Sci. 1980 May 16;289(1036):368-70. Philos Trans R Soc Lond B Biol Sci. 1980. PMID: 6109334 No abstract available.

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