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Imbalance of Endocannabinoid/Lysophosphatidylinositol Receptors Marks the Severity of Alzheimer's Disease in a Preclinical Model: A Therapeutic Opportunity.
Medina-Vera D, Rosell-Valle C, López-Gambero AJ, Navarro JA, Zambrana-Infantes EN, Rivera P, Santín LJ, Suarez J, Rodríguez de Fonseca F. Medina-Vera D, et al. Among authors: zambrana infantes en. Biology (Basel). 2020 Nov 5;9(11):377. doi: 10.3390/biology9110377. Biology (Basel). 2020. PMID: 33167441 Free PMC article.
Effects of the LPA1 Receptor Deficiency and Stress on the Hippocampal LPA Species in Mice.
Tabbai S, Moreno-Fernández RD, Zambrana-Infantes E, Nieto-Quero A, Chun J, García-Fernández M, Estivill-Torrús G, Rodríguez de Fonseca F, Santín LJ, Oliveira TG, Pérez-Martín M, Pedraza C. Tabbai S, et al. Front Mol Neurosci. 2019 Jun 11;12:146. doi: 10.3389/fnmol.2019.00146. eCollection 2019. Front Mol Neurosci. 2019. PMID: 31244601 Free PMC article.
A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration.
González-Gil I, Zian D, Vázquez-Villa H, Hernández-Torres G, Martínez RF, Khiar-Fernández N, Rivera R, Kihara Y, Devesa I, Mathivanan S, Del Valle CR, Zambrana-Infantes E, Puigdomenech M, Cincilla G, Sanchez-Martinez M, Rodríguez de Fonseca F, Ferrer-Montiel AV, Chun J, López-Vales R, López-Rodríguez ML, Ortega-Gutiérrez S. González-Gil I, et al. J Med Chem. 2020 Mar 12;63(5):2372-2390. doi: 10.1021/acs.jmedchem.9b01287. Epub 2019 Dec 16. J Med Chem. 2020. PMID: 31790581 Free PMC article.
Chronic central modulation of LPA/LPA receptors-signaling pathway in the mouse brain regulates cognition, emotion, and hippocampal neurogenesis.
Rosell-Valle C, Pedraza C, Manuel I, Moreno-Rodríguez M, Rodríguez-Puertas R, Castilla-Ortega E, Caramés JM, Gómez Conde AI, Zambrana-Infantes E, Ortega-Pinazo J, Serrano-Castro PJ, Chun J, Rodríguez De Fonseca F, Santín LJ, Estivill-Torrús G. Rosell-Valle C, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jun 8;108:110156. doi: 10.1016/j.pnpbp.2020.110156. Epub 2020 Nov 2. Prog Neuropsychopharmacol Biol Psychiatry. 2021. PMID: 33152386
GABAergic deficits in absence of LPA1 receptor, associated anxiety-like and coping behaviors, and amelioration by interneuron precursor transplants into the dorsal hippocampus.
Rosell-Valle C, Martínez-Losa M, Matas-Rico E, Castilla-Ortega E, Zambrana-Infantes E, Gómez-Conde AI, Sánchez-Salido L, Ladrón de Guevara-Miranda D, Pedraza C, Serrano-Castro PJ, Chun J, Rodríguez de Fonseca F, Álvarez-Dolado M, Santín LJ, Estivill-Torrús G. Rosell-Valle C, et al. Brain Struct Funct. 2021 Jun;226(5):1479-1495. doi: 10.1007/s00429-021-02261-4. Epub 2021 Apr 1. Brain Struct Funct. 2021. PMID: 33792787
Transcending the amyloid-beta dominance paradigm in Alzheimer's disease: An exploration of behavioural, metabolic, and gut microbiota phenotypes in 5xFAD mice.
Medina-Vera D, Zambrana-Infantes EN, López-Gambero AJ, Verheul-Campos J, Santín LJ, Baixeras E, Suarez J, Pavon FJ, Rosell-Valle C, de Fonseca FR. Medina-Vera D, et al. Among authors: zambrana infantes en. Neurobiol Dis. 2023 Oct 15;187:106295. doi: 10.1016/j.nbd.2023.106295. Epub 2023 Sep 16. Neurobiol Dis. 2023. PMID: 37717663 Free article.
12 results