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Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity.
Aging (Albany NY). 2020 Nov 9;12(21):21057-21075. doi: 10.18632/aging.202154. Epub 2020 Nov 9.
Aging (Albany NY). 2020.
PMID: 33168787
Free PMC article.
Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A.
Cuyàs E, Gumuzio J, Lozano-Sánchez J, Carreras D, Verdura S, Llorach-Parés L, Sanchez-Martinez M, Selga E, Pérez GJ, Scornik FS, Brugada R, Bosch-Barrera J, Segura-Carretero A, Martin ÁG, Encinar JA, Menendez JA.
Cuyàs E, et al. Among authors: gumuzio j.
Nutrients. 2019 Jul 19;11(7):1656. doi: 10.3390/nu11071656.
Nutrients. 2019.
PMID: 31331073
Free PMC article.
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The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes.
Cuyàs E, Gumuzio J, Verdura S, Brunet J, Bosch-Barrera J, Martin-Castillo B, Alarcón T, Encinar JA, Martin ÁG, Menendez JA.
Cuyàs E, et al. Among authors: gumuzio j.
Aging (Albany NY). 2020 Mar 18;12(6):4794-4814. doi: 10.18632/aging.102887. Epub 2020 Mar 18.
Aging (Albany NY). 2020.
PMID: 32191225
Free PMC article.
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Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells.
Corominas-Faja B, Cuyàs E, Gumuzio J, Bosch-Barrera J, Leis O, Martin ÁG, Menendez JA.
Corominas-Faja B, et al. Among authors: gumuzio j.
Oncotarget. 2014 Sep 30;5(18):8306-16. doi: 10.18632/oncotarget.2059.
Oncotarget. 2014.
PMID: 25246709
Free PMC article.
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Linking Pluripotency Reprogramming and Cancer.
Iglesias JM, Gumuzio J, Martin AG.
Iglesias JM, et al. Among authors: gumuzio j.
Stem Cells Transl Med. 2017 Feb;6(2):335-339. doi: 10.5966/sctm.2015-0225. Epub 2016 Sep 20.
Stem Cells Transl Med. 2017.
PMID: 28191771
Free PMC article.
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Functional Engagement of the PD-1/PD-L1 Complex But Not PD-L1 Expression Is Highly Predictive of Patient Response to Immunotherapy in Non-Small-Cell Lung Cancer.
Sánchez-Magraner L, Gumuzio J, Miles J, Quimi N, Martínez Del Prado P, Abad-Villar MT, Pikabea F, Ortega L, Etxezarraga C, Martín-Algarra S, Lozano MD, Saiz-Camin M, Egurrola-Izquierdo M, Barredo-Santamaría I, Saiz-López A, Gomez-Mediavilla J, Segues-Merino N, Juaristi-Abaunz MA, Urruticoechea A, Geraedts EJ, van Elst K, Claessens NJM, Italiano A, Applebee CJ, Del Castillo S, Evans C, Aguirre F, Parker PJ, Calleja V.
Sánchez-Magraner L, et al. Among authors: gumuzio j.
J Clin Oncol. 2023 May 10;41(14):2561-2570. doi: 10.1200/JCO.22.01748. Epub 2023 Feb 23.
J Clin Oncol. 2023.
PMID: 36821809
Free PMC article.
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