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Discovery and SAR of Novel Disubstituted Quinazolines as Dual PI3Kalpha/mTOR Inhibitors Targeting Breast Cancer.
ACS Med Chem Lett. 2020 Oct 12;11(11):2156-2164. doi: 10.1021/acsmedchemlett.0c00289. eCollection 2020 Nov 12.
ACS Med Chem Lett. 2020.
PMID: 33214824
Free PMC article.
Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors.
Al-Ashmawy AAK, Ragab FA, Elokely KM, Anwar MM, Perez-Leal O, Rico MC, Gordon J, Bichenkov E, Mateo G, Kassem EMM, Hegazy GH, Abou-Gharbia M, Childers W.
Al-Ashmawy AAK, et al.
Bioorg Med Chem Lett. 2017 Jul 15;27(14):3117-3122. doi: 10.1016/j.bmcl.2017.05.044. Epub 2017 May 15.
Bioorg Med Chem Lett. 2017.
PMID: 28571824
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Synthesis and Characterization of New Dihydronaphthalene Candidates as Potent Cytotoxic Agents against MCF-7 Human Cancer Cells.
Ahmed NS, Sarhan AE, Al-Ashmawy AAK, Amr AEE, Haiba ME, Elsayed EA.
Ahmed NS, et al. Among authors: al ashmawy aak.
Biomed Res Int. 2020 Dec 23;2020:8649745. doi: 10.1155/2020/8649745. eCollection 2020.
Biomed Res Int. 2020.
PMID: 33457417
Free PMC article.
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