Otto TD - Search Results

1

Machine learning approaches classify clinical malaria outcomes based on haematological parameters.

Morang'a CM, Amenga-Etego L, Bah SY, Appiah V, Amuzu DSY, Amoako N, Abugri J, Oduro AR, Cunnington AJ, Awandare GA, Otto TD. Morang'a CM, et al. Among authors: otto td. BMC Med. 2020 Nov 30;18(1):375. doi: 10.1186/s12916-020-01823-3. BMC Med. 2020. PMID: 33250058 Free PMC article.

2

Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution.

Rutledge GG, Böhme U, Sanders M, Reid AJ, Cotton JA, Maiga-Ascofare O, Djimdé AA, Apinjoh TO, Amenga-Etego L, Manske M, Barnwell JW, Renaud F, Ollomo B, Prugnolle F, Anstey NM, Auburn S, Price RN, McCarthy JS, Kwiatkowski DP, Newbold CI, Berriman M, Otto TD. Rutledge GG, et al. Among authors: otto td. Nature. 2017 Feb 2;542(7639):101-104. doi: 10.1038/nature21038. Epub 2017 Jan 25. Nature. 2017. PMID: 28117441 Free PMC article.

3

Transcriptomic Studies of Malaria: a Paradigm for Investigation of Systemic Host-Pathogen Interactions.

Lee HJ, Georgiadou A, Otto TD, Levin M, Coin LJ, Conway DJ, Cunnington AJ. Lee HJ, et al. Among authors: otto td. Microbiol Mol Biol Rev. 2018 Apr 25;82(2):e00071-17. doi: 10.1128/MMBR.00071-17. Print 2018 Jun. Microbiol Mol Biol Rev. 2018. PMID: 29695497 Free PMC article. Review.

4

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria.

Lee HJ, Georgiadou A, Walther M, Nwakanma D, Stewart LB, Levin M, Otto TD, Conway DJ, Coin LJ, Cunnington AJ. Lee HJ, et al. Among authors: otto td. Sci Transl Med. 2018 Jun 27;10(447):eaar3619. doi: 10.1126/scitranslmed.aar3619. Sci Transl Med. 2018. PMID: 29950443 Free PMC article.

5

Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development.

Duffy CW, Amambua-Ngwa A, Ahouidi AD, Diakite M, Awandare GA, Ba H, Tarr SJ, Murray L, Stewart LB, D'Alessandro U, Otto TD, Kwiatkowski DP, Conway DJ. Duffy CW, et al. Among authors: otto td. Sci Rep. 2018 Oct 25;8(1):15763. doi: 10.1038/s41598-018-34078-3. Sci Rep. 2018. PMID: 30361631 Free PMC article.

6

Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum.

Tarr SJ, Díaz-Ingelmo O, Stewart LB, Hocking SE, Murray L, Duffy CW, Otto TD, Chappell L, Rayner JC, Awandare GA, Conway DJ. Tarr SJ, et al. Among authors: otto td. BMC Genomics. 2018 Dec 10;19(1):894. doi: 10.1186/s12864-018-5257-x. BMC Genomics. 2018. PMID: 30526479 Free PMC article.

7

Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions.

Georgiadou A, Lee HJ, Walther M, van Beek AE, Fitriani F, Wouters D, Kuijpers TW, Nwakanma D, D'Alessandro U, Riley EM, Otto TD, Ghani A, Levin M, Coin LJ, Conway DJ, Bretscher MT, Cunnington AJ. Georgiadou A, et al. Among authors: otto td. Nat Microbiol. 2019 Sep;4(9):1592-1602. doi: 10.1038/s41564-019-0474-x. Epub 2019 Jun 17. Nat Microbiol. 2019. PMID: 31209307 Free PMC article.

8

Varia: a tool for prediction, analysis and visualisation of variable genes.

Mackenzie G, Jensen RW, Lavstsen T, Otto TD. Mackenzie G, et al. Among authors: otto td. BMC Bioinformatics. 2022 Jan 24;23(1):52. doi: 10.1186/s12859-022-04573-6. BMC Bioinformatics. 2022. PMID: 35073845 Free PMC article.

9

A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture.

Andradi-Brown C, Wichers-Misterek JS, von Thien H, Höppner YD, Scholz JAM, Hansson H, Filtenborg Hocke E, Gilberger TW, Duffy MF, Lavstsen T, Baum J, Otto TD, Cunnington AJ, Bachmann A. Andradi-Brown C, et al. Among authors: otto td. Elife. 2024 Jan 25;12:RP87726. doi: 10.7554/eLife.87726. Elife. 2024. PMID: 38270586 Free PMC article.

10

Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification.

Oyola SO, Ariani CV, Hamilton WL, Kekre M, Amenga-Etego LN, Ghansah A, Rutledge GG, Redmond S, Manske M, Jyothi D, Jacob CG, Otto TD, Rockett K, Newbold CI, Berriman M, Kwiatkowski DP. Oyola SO, et al. Among authors: otto td. Malar J. 2016 Dec 20;15(1):597. doi: 10.1186/s12936-016-1641-7. Malar J. 2016. PMID: 27998271 Free PMC article.

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