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A substrate binding model for the KEOPS tRNA modifying complex.
Beenstock J, Ona SM, Porat J, Orlicky S, Wan LCK, Ceccarelli DF, Maisonneuve P, Szilard RK, Yin Z, Setiaputra D, Mao DYL, Khan M, Raval S, Schriemer DC, Bayfield MA, Durocher D, Sicheri F. Beenstock J, et al. Among authors: ona sm. Nat Commun. 2020 Dec 4;11(1):6233. doi: 10.1038/s41467-020-19990-5. Nat Commun. 2020. PMID: 33277478 Free PMC article.
Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
Chana CK, Maisonneuve P, Posternak G, Grinberg NGA, Poirson J, Ona SM, Ceccarelli DF, Mader P, St-Cyr DJ, Pau V, Kurinov I, Tang X, Deng D, Cui W, Su W, Kuai L, Soll R, Tyers M, Röst HL, Batey RA, Taipale M, Gingras AC, Sicheri F. Chana CK, et al. Among authors: ona sm. J Med Chem. 2022 Oct 13;65(19):12725-12746. doi: 10.1021/acs.jmedchem.2c00509. Epub 2022 Sep 18. J Med Chem. 2022. PMID: 36117290 Free PMC article.