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Discovery of a Potent and Selective PI3Kδ Inhibitor (S)-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4H-quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models.
Shukla MR, Patra S, Verma M, Sadasivam G, Jana N, Mahangare SJ, Vidhate P, Lagad D, Tarage A, Cheemala M, Kulkarni C, Bhagwat S, Chaudhari VD, Sayyed M, Pachpute V, Phadtare R, Gole G, Phukan S, Sunkara B, Samant C, Shingare M, Naik A, Trivedi S, Marisetti AK, Reddy M, Gholve M, Mahajan N, Sabde S, Patil V, Modi D, Mehta M, Nigade P, Tamane K, Tota S, Goyal H, Volam H, Pawar S, Ahirrao P, Dinchhana L, Mallurwar S, Akarte A, Bokare A, Kanhere R, Reddy N, Koul S, Dandekar M, Singh M, Bernstein PR, Narasimham L, Bhonde M, Gundu J, Goel R, Kulkarni S, Sharma S, Kamboj RK, Palle VP. Shukla MR, et al. Among authors: sayyed m. J Med Chem. 2020 Dec 10;63(23):14700-14723. doi: 10.1021/acs.jmedchem.0c01264. Epub 2020 Dec 1. J Med Chem. 2020. PMID: 33297683
Discovery of LNP1892: A Precision Calcimimetic for the Treatment of Secondary Hyperparathyroidism.
Shukla MR, Sadasivam G, Sarde A, Sayyed M, Pachpute V, Phadtare R, Walke N, Chaudhari VD, Loriya R, Khan T, Gote G, Pawar C, Tryambake M, Mahajan N, Gandhe A, Sabde S, Pawar S, Patil V, Modi D, Mehta M, Nigade P, Modak V, Ghodke R, Narasimham L, Bhonde M, Gundu J, Goel R, Shah C, Kulkarni S, Sharma S, Bakhle D, Kamboj RK, Palle VP. Shukla MR, et al. Among authors: sayyed m. J Med Chem. 2023 Jul 27;66(14):9418-9444. doi: 10.1021/acs.jmedchem.3c00698. Epub 2023 Jul 13. J Med Chem. 2023. PMID: 37442941
Evolution of structural and electronic properties standardized description in rhenium disulfide at the bulk-monolayer transition.
Baglov A, Khoroshko L, Zhoidzik A, Dong M, Weng Q, Kazi M, Khandaker MU, Islam MA, Chowdhury ZZ, Sayyed MI, Trukhanov S, Tishkevich D, Trukhanov A. Baglov A, et al. Among authors: sayyed mi. Heliyon. 2024 Mar 26;10(7):e28646. doi: 10.1016/j.heliyon.2024.e28646. eCollection 2024 Apr 15. Heliyon. 2024. PMID: 38586325 Free PMC article.
123 results