Blundell TL - Search Results

1

HARP: a database of structural impacts of systematic missense mutations in drug targets of Mycobacterium leprae.

Vedithi SC, Malhotra S, Skwark MJ, Munir A, Acebrón-García-De-Eulate M, Waman VP, Alsulami A, Ascher DB, Blundell TL. Vedithi SC, et al. Among authors: blundell tl. Comput Struct Biotechnol J. 2020 Nov 19;18:3692-3704. doi: 10.1016/j.csbj.2020.11.013. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 33304465 Free PMC article.

2

mCSM: predicting the effects of mutations in proteins using graph-based signatures.

Pires DE, Ascher DB, Blundell TL. Pires DE, et al. Among authors: blundell tl. Bioinformatics. 2014 Feb 1;30(3):335-42. doi: 10.1093/bioinformatics/btt691. Epub 2013 Nov 26. Bioinformatics. 2014. PMID: 24281696 Free PMC article.

3

DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach.

Pires DE, Ascher DB, Blundell TL. Pires DE, et al. Among authors: blundell tl. Nucleic Acids Res. 2014 Jul;42(Web Server issue):W314-9. doi: 10.1093/nar/gku411. Epub 2014 May 14. Nucleic Acids Res. 2014. PMID: 24829462 Free PMC article.

4

Platinum: a database of experimentally measured effects of mutations on structurally defined protein-ligand complexes.

Pires DE, Blundell TL, Ascher DB. Pires DE, et al. Among authors: blundell tl. Nucleic Acids Res. 2015 Jan;43(Database issue):D387-91. doi: 10.1093/nar/gku966. Epub 2014 Oct 16. Nucleic Acids Res. 2015. PMID: 25324307 Free PMC article.

5

Flexibility and small pockets at protein-protein interfaces: New insights into druggability.

Jubb H, Blundell TL, Ascher DB. Jubb H, et al. Among authors: blundell tl. Prog Biophys Mol Biol. 2015 Oct;119(1):2-9. doi: 10.1016/j.pbiomolbio.2015.01.009. Epub 2015 Feb 7. Prog Biophys Mol Biol. 2015. PMID: 25662442 Free PMC article. Review.

6

Analysis of HGD Gene Mutations in Patients with Alkaptonuria from the United Kingdom: Identification of Novel Mutations.

Usher JL, Ascher DB, Pires DE, Milan AM, Blundell TL, Ranganath LR. Usher JL, et al. Among authors: blundell tl. JIMD Rep. 2015;24:3-11. doi: 10.1007/8904_2014_380. Epub 2015 Feb 15. JIMD Rep. 2015. PMID: 25681086 Free PMC article.

7

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures.

Pires DE, Blundell TL, Ascher DB. Pires DE, et al. Among authors: blundell tl. J Med Chem. 2015 May 14;58(9):4066-72. doi: 10.1021/acs.jmedchem.5b00104. Epub 2015 Apr 22. J Med Chem. 2015. PMID: 25860834 Free PMC article.

8

Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma.

Jafri M, Wake NC, Ascher DB, Pires DE, Gentle D, Morris MR, Rattenberry E, Simpson MA, Trembath RC, Weber A, Woodward ER, Donaldson A, Blundell TL, Latif F, Maher ER. Jafri M, et al. Among authors: blundell tl. Cancer Discov. 2015 Jul;5(7):723-9. doi: 10.1158/2159-8290.CD-14-1096. Epub 2015 Apr 14. Cancer Discov. 2015. PMID: 25873077

9

Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors.

Blaszczyk M, Harmer NJ, Chirgadze DY, Ascher DB, Blundell TL. Blaszczyk M, et al. Among authors: blundell tl. Prog Biophys Mol Biol. 2015 Sep;118(3):103-11. doi: 10.1016/j.pbiomolbio.2015.04.007. Epub 2015 May 5. Prog Biophys Mol Biol. 2015. PMID: 25957048 Free PMC article. Review.

10

Lst4, the yeast Fnip1/2 orthologue, is a DENN-family protein.

Pacitto A, Ascher DB, Wong LH, Blaszczyk BK, Nookala RK, Zhang N, Dokudovskaya S, Levine TP, Blundell TL. Pacitto A, et al. Among authors: blundell tl. Open Biol. 2015 Dec;5(12):150174. doi: 10.1098/rsob.150174. Open Biol. 2015. PMID: 26631379 Free PMC article.

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