An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease.
Mochizuki H, Hayakawa H, Migita M, Shibata M, Tanaka R, Suzuki A, Shimo-Nakanishi Y, Urabe T, Yamada M, Tamayose K, Shimada T, Miura M, Mizuno Y.
Mochizuki H, et al. Among authors: urabe t.
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10918-23. doi: 10.1073/pnas.191107398. Epub 2001 Sep 4.
Proc Natl Acad Sci U S A. 2001.
PMID: 11535810
Free PMC article.