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Update on CVD 103-HgR single-dose, live oral cholera vaccine.
McCarty J, Bedell L, De Lame PA, Cassie D, Lock M, Bennett S, Haney D. McCarty J, et al. Expert Rev Vaccines. 2022 Jan;21(1):9-23. doi: 10.1080/14760584.2022.2003709. Epub 2021 Dec 27. Expert Rev Vaccines. 2022. PMID: 34775892
Randomized, Placebo-Controlled, Double-Blind Phase 2 Trial Comparing the Reactogenicity and Immunogenicity of a Single Standard Dose to Those of a High Dose of CVD 103-HgR Live Attenuated Oral Cholera Vaccine, with Shanchol Inactivated Oral Vaccine as an Open-Label Immunologic Comparator.
Sow SO, Tapia MD, Chen WH, Haidara FC, Kotloff KL, Pasetti MF, Blackwelder WC, Traoré A, Tamboura B, Doumbia M, Diallo F, Coulibaly F, Onwuchekwa U, Kodio M, Tennant SM, Reymann M, Lam DF, Gurwith M, Lock M, Yonker T, Smith J, Simon JK, Levine MM. Sow SO, et al. Among authors: lock m. Clin Vaccine Immunol. 2017 Dec 5;24(12):e00265-17. doi: 10.1128/CVI.00265-17. Print 2017 Dec. Clin Vaccine Immunol. 2017. PMID: 29021299 Free PMC article. Clinical Trial.
PaxVax CVD 103-HgR single-dose live oral cholera vaccine.
Levine MM, Chen WH, Kaper JB, Lock M, Danzig L, Gurwith M. Levine MM, et al. Expert Rev Vaccines. 2017 Mar;16(3):197-213. doi: 10.1080/14760584.2017.1291348. Expert Rev Vaccines. 2017. PMID: 28165831 Review.
Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-type Vibrio cholerae O1 El Tor Inaba in North American volunteers.
Islam K, Hossain M, Kelly M, Mayo Smith LM, Charles RC, Bhuiyan TR, Kováč P, Xu P, LaRocque RC, Calderwood SB, Simon JK, Chen WH, Haney D, Lock M, Lyon CE, Kirkpatrick BD, Cohen M, Levine MM, Gurwith M, Harris JB, Qadri F, Ryan ET. Islam K, et al. PLoS Negl Trop Dis. 2018 Apr 6;12(4):e0006376. doi: 10.1371/journal.pntd.0006376. eCollection 2018 Apr. PLoS Negl Trop Dis. 2018. PMID: 29624592 Free PMC article. Clinical Trial.
The Live Attenuated Cholera Vaccine CVD 103-HgR Primes Responses to the Toxin-Coregulated Pilus Antigen TcpA in Subjects Challenged with Wild-Type Vibrio cholerae.
Mayo-Smith LM, Simon JK, Chen WH, Haney D, Lock M, Lyon CE, Calderwood SB, Kirkpatrick BD, Cohen M, Levine MM, Gurwith M, Harris JB. Mayo-Smith LM, et al. Clin Vaccine Immunol. 2017 Jan 5;24(1):e00470-16. doi: 10.1128/CVI.00470-16. Print 2017 Jan. Clin Vaccine Immunol. 2017. PMID: 27847368 Free PMC article. Clinical Trial.
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