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Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis.
Shi B, Wang W, Korman B, Kai L, Wang Q, Wei J, Bale S, Marangoni RG, Bhattacharyya S, Miller S, Xu D, Akbarpour M, Cheresh P, Proccissi D, Gursel D, Espindola-Netto JM, Chini CCS, de Oliveira GC, Gudjonsson JE, Chini EN, Varga J. Shi B, et al. Among authors: korman b. iScience. 2020 Dec 7;24(1):101902. doi: 10.1016/j.isci.2020.101902. eCollection 2021 Jan 22. iScience. 2020. PMID: 33385109 Free PMC article.
A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) gene and systemic sclerosis.
Marangoni RG, Korman BD, Allanore Y, Dieude P, Armstrong LL, Rzhetskaya M, Hinchcliff M, Carns M, Podlusky S, Shah SJ, Ruiz B, Hachulla E, Tiev K, Cracowski JL, Varga J, Hayes MG. Marangoni RG, et al. Among authors: korman bd. Arthritis Res Ther. 2015 May 19;17(1):128. doi: 10.1186/s13075-015-0641-2. Arthritis Res Ther. 2015. PMID: 25986483 Free PMC article.
Nrf2 exerts cell-autonomous antifibrotic effects: compromised function in systemic sclerosis and therapeutic rescue with a novel heterocyclic chalcone derivative.
Wei J, Zhu H, Lord G, Bhattachayya M, Jones BM, Allaway G, Biswal SS, Korman B, Marangoni RG, Tourtellotte WG, Varga J. Wei J, et al. Among authors: korman b. Transl Res. 2017 May;183:71-86.e1. doi: 10.1016/j.trsl.2016.12.002. Epub 2016 Dec 9. Transl Res. 2017. PMID: 28027929 Free PMC article.
Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target.
Marangoni RG, Masui Y, Fang F, Korman B, Lord G, Lee J, Lakota K, Wei J, Scherer PE, Otvos L, Yamauchi T, Kubota N, Kadowaki T, Asano Y, Sato S, Tourtellotte WG, Varga J. Marangoni RG, et al. Among authors: korman b. Sci Rep. 2017 Jun 30;7(1):4397. doi: 10.1038/s41598-017-04162-1. Sci Rep. 2017. PMID: 28667272 Free PMC article.
93 results