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Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity.
Nat Commun. 2021 Jan 4;12(1):81. doi: 10.1038/s41467-020-20439-y.
Nat Commun. 2021.
PMID: 33398055
Free PMC article.
Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model.
Proud PC, Tsitoura D, Watson RJ, Chua BY, Aram MJ, Bewley KR, Cavell BE, Cobb R, Dowall S, Fotheringham SA, Ho CMK, Lucas V, Ngabo D, Rayner E, Ryan KA, Slack GS, Thomas S, Wand NI, Yeates P, Demaison C, Zeng W, Holmes I, Jackson DC, Bartlett NW, Mercuri F, Carroll MW.
Proud PC, et al. Among authors: aram mj.
EBioMedicine. 2021 Jan;63:103153. doi: 10.1016/j.ebiom.2020.103153. Epub 2020 Dec 3.
EBioMedicine. 2021.
PMID: 33279857
Free PMC article.
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Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19.
Salguero FJ, White AD, Slack GS, Fotheringham SA, Bewley KR, Gooch KE, Longet S, Humphries HE, Watson RJ, Hunter L, Ryan KA, Hall Y, Sibley L, Sarfas C, Allen L, Aram M, Brunt E, Brown P, Buttigieg KR, Cavell BE, Cobb R, Coombes NS, Darby A, Daykin-Pont O, Elmore MJ, Garcia-Dorival I, Gkolfinos K, Godwin KJ, Gouriet J, Halkerston R, Harris DJ, Hender T, Ho CMK, Kennard CL, Knott D, Leung S, Lucas V, Mabbutt A, Morrison AL, Nelson C, Ngabo D, Paterson J, Penn EJ, Pullan S, Taylor I, Tipton T, Thomas S, Tree JA, Turner C, Vamos E, Wand N, Wiblin NR, Charlton S, Dong X, Hallis B, Pearson G, Rayner EL, Nicholson AG, Funnell SG, Hiscox JA, Dennis MJ, Gleeson FV, Sharpe S, Carroll MW.
Salguero FJ, et al. Among authors: aram m.
Nat Commun. 2021 Feb 24;12(1):1260. doi: 10.1038/s41467-021-21389-9.
Nat Commun. 2021.
PMID: 33627662
Free PMC article.
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ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models.
Lambe T, Spencer AJ, Thomas KM, Gooch KE, Thomas S, White AD, Humphries HE, Wright D, Belij-Rammerstorfer S, Thakur N, Conceicao C, Watson R, Alden L, Allen L, Aram M, Bewley KR, Brunt E, Brown P, Cavell BE, Cobb R, Fotheringham SA, Gilbride C, Harris DJ, Ho CMK, Hunter L, Kennard CL, Leung S, Lucas V, Ngabo D, Ryan KA, Sharpe H, Sarfas C, Sibley L, Slack GS, Ulaszewska M, Wand N, Wiblin NR, Gleeson FV, Bailey D, Sharpe S, Charlton S, Salguero FJ, Carroll MW, Gilbert SC.
Lambe T, et al.
Commun Biol. 2021 Jul 26;4(1):915. doi: 10.1038/s42003-021-02443-0.
Commun Biol. 2021.
PMID: 34312487
Free PMC article.
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Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques.
Bewley KR, Gooch K, Thomas KM, Longet S, Wiblin N, Hunter L, Chan K, Brown P, Russell RA, Ho C, Slack G, Humphries HE, Alden L, Allen L, Aram M, Baker N, Brunt E, Cobb R, Fotheringham S, Harris D, Kennard C, Leung S, Ryan K, Tolley H, Wand N, White A, Sibley L, Sarfas C, Pearson G, Rayner E, Xue X, Lambe T, Charlton S, Gilbert S, Sattentau QJ, Gleeson F, Hall Y, Funnell S, Sharpe S, Salguero FJ, Gorringe A, Carroll M.
Bewley KR, et al.
Sci Adv. 2021 Sep 10;7(37):eabg7996. doi: 10.1126/sciadv.abg7996. Epub 2021 Sep 10.
Sci Adv. 2021.
PMID: 34516768
Free PMC article.
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Hantavirus infection in type I interferon receptor-deficient (A129) mice.
Dowall SD, Graham VA, Aram M, Findlay-Wilson S, Salguero FJ, Emery K, Hewson R.
Dowall SD, et al.
J Gen Virol. 2020 Oct;101(10):1047-1055. doi: 10.1099/jgv.0.001470.
J Gen Virol. 2020.
PMID: 32667279
Free PMC article.
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A vaccine based on recombinant modified Vaccinia Ankara containing the nucleoprotein from Lassa virus protects against disease progression in a guinea pig model.
Kennedy EM, Dowall SD, Salguero FJ, Yeates P, Aram M, Hewson R.
Kennedy EM, et al.
Vaccine. 2019 Aug 23;37(36):5404-5413. doi: 10.1016/j.vaccine.2019.07.023. Epub 2019 Jul 19.
Vaccine. 2019.
PMID: 31331770
Free article.
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Autochthonous tick-borne encephalitis in the United Kingdom: A second probable human case and local eco-epidemiological findings.
Mansbridge CT, Osborne J, Holding M, Dryden M, Aram M, Brown K, Sutton J.
Mansbridge CT, et al.
Ticks Tick Borne Dis. 2022 Jan;13(1):101853. doi: 10.1016/j.ttbdis.2021.101853. Epub 2021 Oct 10.
Ticks Tick Borne Dis. 2022.
PMID: 34670189
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