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Droplet-based mRNA sequencing of fixed and permeabilized cells by CLInt-seq allows for antigen-specific TCR cloning.
Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2021190118. doi: 10.1073/pnas.2021190118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33431692
Free PMC article.
HLA-A∗02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses.
Nesterenko PA, McLaughlin J, Tsai BL, Burton Sojo G, Cheng D, Zhao D, Mao Z, Bangayan NJ, Obusan MB, Su Y, Ng RH, Chour W, Xie J, Li YR, Lee D, Noguchi M, Carmona C, Phillips JW, Kim JT, Yang L, Heath JR, Boutros PC, Witte ON.
Nesterenko PA, et al.
Cell Rep. 2021 Dec 28;37(13):110167. doi: 10.1016/j.celrep.2021.110167. Epub 2021 Dec 10.
Cell Rep. 2021.
PMID: 34919800
Free PMC article.
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Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation.
Mao Z, Nesterenko PA, McLaughlin J, Deng W, Burton Sojo G, Cheng D, Noguchi M, Chour W, DeLucia DC, Finton KA, Qin Y, Obusan MB, Tran W, Wang L, Bangayan NJ, Ta L, Chen CC, Seet CS, Crooks GM, Phillips JW, Heath JR, Strong RK, Lee JK, Wohlschlegel JA, Witte ON.
Mao Z, et al. Among authors: nesterenko pa.
Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2203410119. doi: 10.1073/pnas.2203410119. Epub 2022 Jul 25.
Proc Natl Acad Sci U S A. 2022.
PMID: 35878026
Free PMC article.
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IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing.
Pan Y, Phillips JW, Zhang BD, Noguchi M, Kutschera E, McLaughlin J, Nesterenko PA, Mao Z, Bangayan NJ, Wang R, Tran W, Yang HT, Wang Y, Xu Y, Obusan MB, Cheng D, Lee AH, Kadash-Edmondson KE, Champhekar A, Puig-Saus C, Ribas A, Prins RM, Seet CS, Crooks GM, Witte ON, Xing Y.
Pan Y, et al. Among authors: nesterenko pa.
Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2221116120. doi: 10.1073/pnas.2221116120. Epub 2023 May 16.
Proc Natl Acad Sci U S A. 2023.
PMID: 37192158
Free PMC article.
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Latent CMV infection of Lymphatic endothelial cells is sufficient to drive CD8 T cell memory inflation.
Munks MW, Rott K, Nesterenko PA, Smart SM, Williams V, Tatum A, Xu G, Smith T, Murray SE, Hill AB.
Munks MW, et al. Among authors: nesterenko pa.
PLoS Pathog. 2023 Jan 23;19(1):e1010351. doi: 10.1371/journal.ppat.1010351. eCollection 2023 Jan.
PLoS Pathog. 2023.
PMID: 36689486
Free PMC article.
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Fibroblast-adapted human CMV vaccines elicit predominantly conventional CD8 T cell responses in humans.
Murray SE, Nesterenko PA, Vanarsdall AL, Munks MW, Smart SM, Veziroglu EM, Sagario LC, Lee R, Claas FHJ, Doxiadis IIN, McVoy MA, Adler SP, Hill AB.
Murray SE, et al. Among authors: nesterenko pa.
J Exp Med. 2017 Jul 3;214(7):1889-1899. doi: 10.1084/jem.20161988. Epub 2017 May 31.
J Exp Med. 2017.
PMID: 28566275
Free PMC article.
Clinical Trial.
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A Phase 1 Study of 4 Live, Recombinant Human Cytomegalovirus Towne/Toledo Chimera Vaccines in Cytomegalovirus-Seronegative Men.
Adler SP, Manganello AM, Lee R, McVoy MA, Nixon DE, Plotkin S, Mocarski E, Cox JH, Fast PE, Nesterenko PA, Murray SE, Hill AB, Kemble G.
Adler SP, et al. Among authors: nesterenko pa.
J Infect Dis. 2016 Nov 1;214(9):1341-1348. doi: 10.1093/infdis/jiw365. Epub 2016 Aug 11.
J Infect Dis. 2016.
PMID: 27521362
Free PMC article.
Clinical Trial.
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