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Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases.
Barturen G, Babaei S, Català-Moll F, Martínez-Bueno M, Makowska Z, Martorell-Marugán J, Carmona-Sáez P, Toro-Domínguez D, Carnero-Montoro E, Teruel M, Kerick M, Acosta-Herrera M, Le Lann L, Jamin C, Rodríguez-Ubreva J, García-Gómez A, Kageyama J, Buttgereit A, Hayat S, Mueller J, Lesche R, Hernandez-Fuentes M, Juarez M, Rowley T, White I, Marañón C, Gomes Anjos T, Varela N, Aguilar-Quesada R, Garrancho FJ, López-Berrio A, Rodriguez Maresca M, Navarro-Linares H, Almeida I, Azevedo N, Brandão M, Campar A, Faria R, Farinha F, Marinho A, Neves E, Tavares A, Vasconcelos C, Trombetta E, Montanelli G, Vigone B, Alvarez-Errico D, Li T, Thiagaran D, Blanco Alonso R, Corrales Martínez A, Genre F, López Mejías R, Gonzalez-Gay MA, Remuzgo S, Ubilla Garcia B, Cervera R, Espinosa G, Rodríguez-Pintó I, De Langhe E, Cremer J, Lories R, Belz D, Hunzelmann N, Baerlecken N, Kniesch K, Witte T, Lehner M, Stummvoll G, Zauner M, Aguirre-Zamorano MA, Barbarroja N, Castro-Villegas MC, Collantes-Estevez E, de Ramon E, Díaz Quintero I, Escudero-Contreras A, Fernández Roldán MC, Jiménez Gómez Y, Jiménez Moleón I, Lopez-Pedrera R, Ortega-Castro R, Ortego N, Raya E, Artusi C, Gerosa M, Meroni PL, Schio… See abstract for full author list ➔ Barturen G, et al. Among authors: li t. Arthritis Rheumatol. 2021 Jun;73(6):1073-1085. doi: 10.1002/art.41610. Epub 2021 Apr 26. Arthritis Rheumatol. 2021. PMID: 33497037 Free article.
TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells.
Garcia-Gomez A, Li T, Kerick M, Català-Moll F, Comet NR, Rodríguez-Ubreva J, de la Rica L, Branco MR, Martín J, Ballestar E. Garcia-Gomez A, et al. Among authors: li t. Nucleic Acids Res. 2017 Sep 29;45(17):10002-10017. doi: 10.1093/nar/gkx666. Nucleic Acids Res. 2017. PMID: 28973458 Free PMC article.
Inflammatory cytokines shape a changing DNA methylome in monocytes mirroring disease activity in rheumatoid arthritis.
Rodríguez-Ubreva J, de la Calle-Fabregat C, Li T, Ciudad L, Ballestar ML, Català-Moll F, Morante-Palacios O, Garcia-Gomez A, Celis R, Humby F, Nerviani A, Martin J, Pitzalis C, Cañete JD, Ballestar E. Rodríguez-Ubreva J, et al. Among authors: li t. Ann Rheum Dis. 2019 Nov;78(11):1505-1516. doi: 10.1136/annrheumdis-2019-215355. Epub 2019 Aug 1. Ann Rheum Dis. 2019. PMID: 31371305
Genome-wide whole blood transcriptome profiling in a large European cohort of systemic sclerosis patients.
Beretta L, Barturen G, Vigone B, Bellocchi C, Hunzelmann N, De Langhe E, Cervera R, Gerosa M, Kovács L, Ortega Castro R, Almeida I, Cornec D, Chizzolini C, Pers JO, Makowska Z, Lesche R, Kerick M, Alarcón-Riquelme ME, Martin J; PRECISESADS SSc substudy group; PRECISESADS Flow Cytometry study group. Beretta L, et al. Ann Rheum Dis. 2020 Sep;79(9):1218-1226. doi: 10.1136/annrheumdis-2020-217116. Epub 2020 Jun 19. Ann Rheum Dis. 2020. PMID: 32561607 Free PMC article.
Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci.
Li T, Ortiz-Fernández L, Andrés-León E, Ciudad L, Javierre BM, López-Isac E, Guillén-Del-Castillo A, Simeón-Aznar CP, Ballestar E, Martin J. Li T, et al. Genome Med. 2020 Sep 25;12(1):81. doi: 10.1186/s13073-020-00779-6. Genome Med. 2020. PMID: 32977850 Free PMC article.
Genomic Risk Score impact on susceptibility to systemic sclerosis.
Bossini-Castillo L, Villanueva-Martin G, Kerick M, Acosta-Herrera M, López-Isac E, Simeón CP, Ortego-Centeno N, Assassi S; International SSc Group; Australian Scleroderma Interest Group (ASIG); PRECISESADS Clinical Consortium; PRECISESADS Flow Cytometry study group; Hunzelmann N, Gabrielli A, de Vries-Bouwstra JK, Allanore Y, Fonseca C, Denton CP, Radstake TR, Alarcón-Riquelme ME, Beretta L, Mayes MD, Martin J. Bossini-Castillo L, et al. Ann Rheum Dis. 2021 Jan;80(1):118-127. doi: 10.1136/annrheumdis-2020-218558. Epub 2020 Oct 1. Ann Rheum Dis. 2021. PMID: 33004331 Free article.
A Proinflammatory Cytokine Network Profile in Th1/Type 1 Effector B Cells Delineates a Common Group of Patients in Four Systemic Autoimmune Diseases.
Simon Q, Grasseau A, Boudigou M, Le Pottier L, Bettachioli E, Cornec D, Rouvière B, Jamin C, Le Lann L; PRECISESADS Clinical Consortium; PRECISESADS Flow Cytometry Study Group; Borghi MO, Aguilar-Quesada R, Renaudineau Y, Alarcón-Riquelme ME, Pers JO, Hillion S. Simon Q, et al. Arthritis Rheumatol. 2021 Aug;73(8):1550-1561. doi: 10.1002/art.41697. Epub 2021 Jul 9. Arthritis Rheumatol. 2021. PMID: 33605069
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