van Ingen E - Search Results

1

Characterization of Pharmacokinetics, Biotransformation and Elimination of Pomotrelvir Orally Administered in Healthy Male Adults Using Two [¹⁴C]-Labeled Microtracers with Separate Labeling Positions.

Yang Z, Wong SL, Cha D, Wilfret D, Turnquist D, Plummer A, van Ingen E, Kearney BP. Yang Z, et al. Among authors: van ingen e. Drug Metab Dispos. 2023 Dec;51(12):1607-1614. doi: 10.1124/dmd.123.001439. Epub 2023 Sep 8. Drug Metab Dispos. 2023. PMID: 37684056

2

Single-cell profiling reveals age-associated immunity in atherosclerosis.

Smit V, de Mol J, Schaftenaar FH, Depuydt MAC, Postel RJ, Smeets D, Verheijen FWM, Bogers L, van Duijn J, Verwilligen RAF, Grievink HW, Bernabé Kleijn MNA, van Ingen E, de Jong MJM, Goncalves L, Peeters JAHM, Smeets HJ, Wezel A, Polansky JK, de Winther MPJ, Binder CJ, Tsiantoulas D, Bot I, Kuiper J, Foks AC. Smit V, et al. Among authors: van ingen e. Cardiovasc Res. 2023 Nov 25;119(15):2508-2521. doi: 10.1093/cvr/cvad099. Cardiovasc Res. 2023. PMID: 37390467 Free PMC article.

3

C/D box snoRNA SNORD113-6 guides 2'-O-methylation and protects against site-specific fragmentation of tRNA^Leu(TAA) in vascular remodeling.

van Ingen E, Engbers PAM, Woudenberg T, van der Bent ML, Mei H, Wojta J, Quax PHA, Nossent AY. van Ingen E, et al. Mol Ther Nucleic Acids. 2022 Sep 17;30:162-172. doi: 10.1016/j.omtn.2022.09.011. eCollection 2022 Dec 13. Mol Ther Nucleic Acids. 2022. PMID: 36250206 Free PMC article.

4

The long non-coding RNA MEG8 induces an endothelial barrier through regulation of microRNA-370 and -494 processing.

Kremer V, Stanicek L, van Ingen E, Bink DI, Hilderink S, Tijsen AJ, Wittig I, Mägdefessel L, Nossent AY, Boon RA. Kremer V, et al. Among authors: van ingen e. J Cell Sci. 2022 Jun 15;135(12):jcs259671. doi: 10.1242/jcs.259671. Epub 2022 Jun 16. J Cell Sci. 2022. PMID: 35611612 Free PMC article.

5

MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium.

Kremer V, Bink DI, Stanicek L, van Ingen E, Gimbel T, Hilderink S, Günther S, Nossent AY, Boon RA. Kremer V, et al. Among authors: van ingen e. Sci Rep. 2022 Jan 17;12(1):843. doi: 10.1038/s41598-022-04812-z. Sci Rep. 2022. PMID: 35039572 Free PMC article.

6

Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis.

van Ingen E, Foks AC, Woudenberg T, van der Bent ML, de Jong A, Hohensinner PJ, Wojta J, Bot I, Quax PHA, Nossent AY. van Ingen E, et al. Mol Ther Nucleic Acids. 2021 Nov 4;26:1228-1239. doi: 10.1016/j.omtn.2021.10.027. eCollection 2021 Dec 3. Mol Ther Nucleic Acids. 2021. PMID: 34853722 Free PMC article.

7

C/D box snoRNA SNORD113-6/AF357425 plays a dual role in integrin signalling and arterial fibroblast function via pre-mRNA processing and 2'O-ribose methylation.

van Ingen E, van den Homberg DAL, van der Bent ML, Mei H, Papac-Milicevic N, Kremer V, Boon RA, Quax PHA, Wojta J, Nossent AY. van Ingen E, et al. Hum Mol Genet. 2022 Mar 31;31(7):1051-1066. doi: 10.1093/hmg/ddab304. Hum Mol Genet. 2022. PMID: 34673944 Free PMC article.

8

Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies.

Xiao D, John Ling KH, Tarnowski T, Humeniuk R, German P, Mathias A, Chu J, Chen YS, van Ingen E. Xiao D, et al. Among authors: van ingen e. Anal Biochem. 2021 Mar 15;617:114118. doi: 10.1016/j.ab.2021.114118. Epub 2021 Jan 26. Anal Biochem. 2021. PMID: 33508271 Free PMC article.

9

Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia.

van der Kwast RVCT, Parma L, van der Bent ML, van Ingen E, Baganha F, Peters HAB, Goossens EAC, Simons KH, Palmen M, de Vries MR, Quax PHA, Nossent AY. van der Kwast RVCT, et al. Among authors: van ingen e. Mol Ther Nucleic Acids. 2020 Sep 4;21:932-953. doi: 10.1016/j.omtn.2020.07.020. Epub 2020 Jul 21. Mol Ther Nucleic Acids. 2020. PMID: 32814251 Free PMC article.

10

Antisense Oligonucleotide Inhibition of MicroRNA-494 Halts Atherosclerotic Plaque Progression and Promotes Plaque Stabilization.

van Ingen E, Foks AC, Kröner MJ, Kuiper J, Quax PHA, Bot I, Nossent AY. van Ingen E, et al. Mol Ther Nucleic Acids. 2019 Dec 6;18:638-649. doi: 10.1016/j.omtn.2019.09.021. Epub 2019 Sep 30. Mol Ther Nucleic Acids. 2019. PMID: 31689618 Free PMC article.

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